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Julia Romani

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Articles 8
Citations 174
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Recent Articles
1.
Quentmeier H, Pommerenke C, Ammerpohl O, Geffers R, Hauer V, MacLeod R, et al.
Oncotarget . 2016 Aug; 7(39):63456-63465. PMID: 27566572
Genetic heterogeneity though common in tumors has been rarely documented in cell lines. To examine how often B-lymphoma cell lines are comprised of subclones, we performed immunoglobulin (IG) heavy chain...
2.
Ding J, Dirks W, Ehrentraut S, Geffers R, MacLeod R, Nagel S, et al.
Haematologica . 2015 Mar; 100(6):801-9. PMID: 25769544
Genetic heterogeneity is widespread in tumors, but poorly documented in cell lines. According to immunoglobulin hypermutation analysis, the diffuse large B-cell lymphoma cell line U-2932 comprises two subpopulations faithfully representing...
3.
Ding J, Romani J, Zaborski M, MacLeod R, Nagel S, Drexler H, et al.
PLoS One . 2013 Dec; 8(12):e83510. PMID: 24349524
Chronic myeloid leukemia (CML) is a cytogenetic disorder resulting from formation of the Philadelphia chromosome (Ph), that is, the t(9;22) chromosomal translocation and the formation of the BCR-ABL1 fusion protein....
4.
Quentmeier H, Eberth S, Romani J, Weich H, Zaborski M, Drexler H
BMC Cancer . 2012 Jan; 12:19. PMID: 22251800
Background: Vascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on...
5.
Quentmeier H, Eberth S, Romani J, Zaborski M, Drexler H
J Hematol Oncol . 2011 Feb; 4:6. PMID: 21299849
Background: The BCR-ABL1 translocation occurs in chronic myeloid leukemia (CML) and in 25% of cases with acute lymphoblastic leukemia (ALL). The advent of tyrosine kinase inhibitors (TKI) has fundamentally changed...
6.
Eberth S, Schneider B, Rosenwald A, Hartmann E, Romani J, Zaborski M, et al.
BMC Cancer . 2010 Oct; 10:517. PMID: 20920234
Background: Epigenetic inactivation of tumor suppressor genes (TSG) by promoter CpG island hypermethylation is a hallmark of cancer. To assay its extent in human lymphoma, methylation of 24 TSG was...
7.
Rohrs S, Scherr M, Romani J, Zaborski M, Drexler H, Quentmeier H
J Hematol Oncol . 2010 Apr; 3:15. PMID: 20398252
Background: CD7 is a negative prognostic marker in myeloid malignancies. In acute myeloid leukemia (AML), an inverse correlation exists between expression of wild-type CEBPA and CD7. Aim of this study...
8.
Quentmeier H, Schneider B, Rohrs S, Romani J, Zaborski M, MacLeod R, et al.
J Hematol Oncol . 2009 Jan; 2:3. PMID: 19166587
Background: SET-NUP214 fusion resulting from a recurrent cryptic deletion, del(9)(q34.11q34.13) has recently been described in T-cell acute lymphoblastic leukemia (T-ALL) and in one case of acute myeloid leukemia (AML). The...