Julia Patzig
Overview
Explore the profile of Julia Patzig including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
443
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Recent Articles
1.
Pruvost M, Patzig J, Yattah C, Selcen I, Hernandez M, Park H, et al.
Cell Rep
. 2023 Jul;
42(8):112848.
PMID: 37515770
Oligodendrocytes are specialized cells that insulate and support axons with their myelin membrane, allowing proper brain function. Here, we identify lamin A/C (LMNA/C) as essential for transcriptional and functional stability...
2.
Martens A, Erwig M, Patzig J, Fledrich R, Fuchtbauer E, Werner H
Cytoskeleton (Hoboken)
. 2022 Nov;
80(7-8):290-302.
PMID: 36378242
The formation of axon-enwrapping myelin sheaths by oligodendrocytes in the central nervous system involves the assembly of a scaffolding septin filament comprised of the subunits SEPTIN2, SEPTIN4, SEPTIN7 and SEPTIN8....
3.
Park H, Tsai E, Huang D, Weaver M, Frick L, Alcantara A, et al.
iScience
. 2022 Apr;
25(4):104132.
PMID: 35434551
Cells elaborate transcriptional programs in response to external signals. In the peripheral nerves, Schwann cells (SC) sort axons of given caliber and start the process of wrapping their membrane around...
4.
Marechal D, Dansu D, Castro K, Patzig J, Magri L, Inbar B, et al.
Glia
. 2021 Oct;
70(2):321-336.
PMID: 34687571
The N-myc downstream regulated gene family member 1 (NDRG1) is a gene whose mutation results in peripheral neuropathy with central manifestations. While most of previous studies characterized NDRG1 role in...
5.
Erwig M, Patzig J, Steyer A, Dibaj P, Heilmann M, Heilmann I, et al.
Elife
. 2019 Jan;
8.
PMID: 30672734
Myelin serves as an axonal insulator that facilitates rapid nerve conduction along axons. By transmission electron microscopy, a healthy myelin sheath comprises compacted membrane layers spiraling around the cross-sectioned axon....
6.
Luders K, Nessler S, Kusch K, Patzig J, Jung R, Mobius W, et al.
Glia
. 2019 Jan;
67(4):634-649.
PMID: 30637801
Proteolipid protein (PLP) is the most abundant integral membrane protein in central nervous system (CNS) myelin. Expression of the Plp-gene in oligodendrocytes is not essential for the biosynthesis of myelin...
7.
Scaglione A, Patzig J, Liang J, Frawley R, Bok J, Mela A, et al.
Nat Commun
. 2018 Jul;
9(1):2840.
PMID: 30026560
Oligodendrocytes (OLs) are the myelin-forming cells of the central nervous system. They are derived from differentiation of oligodendrocyte progenitors through a process requiring cell cycle exit and histone modifications. Here...
8.
Luders K, Patzig J, Simons M, Nave K, Werner H
Glia
. 2017 Aug;
65(11):1762-1776.
PMID: 28836307
Proteolipid protein (PLP) is the most abundant integral membrane protein in compact central nervous system myelin, and null mutations of the PLP1 gene cause spastic paraplegia type 2 (SPG2). SPG2...
9.
Patzig J, Erwig M, Tenzer S, Kusch K, Dibaj P, Mobius W, et al.
Elife
. 2016 Aug;
5.
PMID: 27504968
Myelination of axons facilitates rapid impulse propagation in the nervous system. The axon/myelin-unit becomes impaired in myelin-related disorders and upon normal aging. However, the molecular cause of many pathological features,...
10.
Hernandez M, Patzig J, Mayoral S, Costa K, Chan J, Casaccia P
J Neurosci
. 2016 Jan;
36(3):806-13.
PMID: 26791211
Oligodendrocyte progenitors respond to biophysical or mechanical signals, and it has been reported that mechanostimulation modulates cell proliferation, migration, and differentiation. Here we report the effect of three mechanical stimuli...