Julia Lohman
Overview
Explore the profile of Julia Lohman including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
75
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Boezio A, Copeland K, Rex K, Albrecht B, Bauer D, Bellon S, et al.
J Med Chem
. 2016 Jan;
59(6):2328-42.
PMID: 26812066
Deregulation of the receptor tyrosine kinase mesenchymal epithelial transition factor (MET) has been implicated in several human cancers and is an attractive target for small molecule drug discovery. Herein, we...
2.
Peterson E, Teffera Y, Albrecht B, Bauer D, Bellon S, Boezio A, et al.
J Med Chem
. 2015 Apr;
58(9):4087.
PMID: 25901648
No abstract available.
3.
Peterson E, Teffera Y, Albrecht B, Bauer D, Bellon S, Boezio A, et al.
J Med Chem
. 2015 Feb;
58(5):2417-30.
PMID: 25699405
The overexpression of c-Met and/or hepatocyte growth factor (HGF), the amplification of the MET gene, and mutations in the c-Met kinase domain can activate signaling pathways that contribute to cancer...
4.
Gonzalez-Lopez de Turiso F, Shin Y, Brown M, Cardozo M, Chen Y, Fong D, et al.
J Med Chem
. 2012 Aug;
55(17):7667-85.
PMID: 22876881
Structure-based rational design led to the synthesis of a novel series of potent PI3K inhibitors. The optimized pyrrolopyridine analogue 63 was a potent and selective PI3Kβ/δ dual inhibitor that displayed...
5.
Boezio A, Berry L, Albrecht B, Bauer D, Bellon S, Bode C, et al.
Bioorg Med Chem Lett
. 2009 Oct;
19(22):6307-12.
PMID: 19819693
Deregulation of the receptor tyrosine kinase c-Met has been implicated in several human cancers and is an attractive target for small molecule drug discovery. We previously showed that O-linked triazolopyridazines...
6.
Albrecht B, Harmange J, Bauer D, Berry L, Bode C, Boezio A, et al.
J Med Chem
. 2008 Apr;
51(10):2879-82.
PMID: 18426196
Tumorigenesis is a multistep process in which oncogenes play a key role in tumor formation, growth, and maintenance. MET was discovered as an oncogene that is activated by its ligand,...
7.
Tai V, Sperandio D, Shelton E, Litvak J, Pararajasingham K, Cebon B, et al.
Bioorg Med Chem Lett
. 2006 Jun;
16(17):4554-8.
PMID: 16784854
As a continuation of our efforts to discover novel apoptosis inducers as anticancer agents using a cell-based caspase HTS assay, 2-phenyl-oxazole-4-carboxamide derivatives were identified. The structure-activity relationships of this class...
8.
Sperandio D, Tai V, Lohman J, Hirschbein B, Mendonca R, Lee C, et al.
Bioorg Med Chem Lett
. 2006 May;
16(15):4085-9.
PMID: 16725321
The synthesis of novel [1,2,4]oxadiazoles and their structure-activity relationship (SAR) for the inhibition of tryptase and related serine proteases is presented. Elaboration of the P'-side afforded potent, selective, and orally...
9.
Palmer J, Rydzewski R, Mendonca R, Sperandio D, Spencer J, Hirschbein B, et al.
Bioorg Med Chem Lett
. 2006 Apr;
16(13):3434-9.
PMID: 16644215
Using a scaleable, directed library approach based on orthogonally protected advanced intermediates, we have prepared a series of potent keto-1,2,4-oxadiazoles designed to explore the P(2) binding pocket of human mast...
10.
Ouyang X, Piatnitski E, Pattaropong V, Chen X, He H, Kiselyov A, et al.
Bioorg Med Chem Lett
. 2005 Dec;
16(5):1191-6.
PMID: 16377187
Oxadiazole derivatives were synthesized and evaluated for their ability to inhibit tubulin polymerization and to cause mitotic arrest in tumor cells. The most potent compounds inhibited tubulin polymerization at concentrations...