Julia Lefler
Overview
Explore the profile of Julia Lefler including associated specialties, affiliations and a list of published articles.
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5
Citations
51
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0
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Recent Articles
1.
Akkapeddi P, Hattori T, Khan I, Glasser E, Koide A, Ketavarapu G, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(28):e2302485120.
PMID: 37399416
The G12D mutation is among the most common KRAS mutations associated with cancer, in particular, pancreatic cancer. Here, we have developed monobodies, small synthetic binding proteins, that are selective to...
2.
Han L, Wu Y, Fang K, Sweeney S, Roesner U, Parrish M, et al.
Nat Commun
. 2023 Jan;
14(1):1.
PMID: 36596776
Pancreatic cancer is characterized by abundant desmoplasia, a dense stroma composed of extra-cellular and cellular components, with cancer associated fibroblasts (CAFs) being the major cellular component. However, the tissue(s) of...
3.
Rujchanarong D, Lefler J, Saunders J, Pippin S, Spruill L, Bethard J, et al.
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503228
Breast stroma plays a significant role in breast cancer risk and progression yet remains poorly understood. In breast stroma, collagen is the most abundantly expressed protein and its increased deposition...
4.
Khan I, Marelia-Bennet C, Lefler J, Zuberi M, Denbaum E, Koide A, et al.
Small GTPases
. 2021 May;
13(1):114-127.
PMID: 33949915
is the most frequently mutated oncogene in human cancer with nearly ~20% of cancer patients possessing mutations in one of three genes ( or ). However, is mutated in nearly...
5.
Willyard A, Gernandt D, Potter K, Hipkins V, Marquardt P, Mahalovich M, et al.
Am J Bot
. 2016 Dec;
104(1):161-181.
PMID: 28031167
Premise Of The Study: Molecular genetic evidence can help delineate taxa in species complexes that lack diagnostic morphological characters. Pinus ponderosa (Pinaceae; subsection Ponderosae) is recognized as a problematic taxon:...