Julia Kargl
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Explore the profile of Julia Kargl including associated specialties, affiliations and a list of published articles.
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51
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1905
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Recent Articles
1.
Ristic D, Barnthaler T, Gruden E, Kienzl M, Danner L, Herceg K, et al.
Front Immunol
. 2025 Jan;
15:1513547.
PMID: 39885986
Background: The G protein-coupled receptor 55 (GPR55) is part of an expanded endocannabinoid system (ECS), and plays a pro-tumorigenic role in different cancer models, including pancreatic cancer. Next to cancer...
2.
Zotta A, Toller-Kawahisa J, Palsson-McDermott E, OCarroll S, Henry O, Day E, et al.
Sci Adv
. 2025 Jan;
11(4):eadq7307.
PMID: 39841829
The cytokine interleukin-10 (IL-10) limits the immune response and promotes resolution of acute inflammation. Because of its immunosuppressive effects, IL-10 up-regulation is a common feature of tumor progression and metastasis....
3.
Lyssy F, Forstner D, Brugger B, Ujcic K, Guettler J, Kupper N, et al.
Placenta
. 2024 May;
PMID: 38705802
The study of very early human placentation is largely limited due to ethical restrictions on the use of embryonic tissue and the fact that the placental anatomy of common laboratory...
4.
Prostaglandin E2 in the Tumor Microenvironment, a Convoluted Affair Mediated by EP Receptors 2 and 4
Santiso A, Heinemann A, Kargl J
Pharmacol Rev
. 2024 May;
76(3):388-413.
PMID: 38697857
The involvement of the prostaglandin E2 (PGE2) system in cancer progression has long been recognized. PGE2 functions as an autocrine and paracrine signaling molecule with pleiotropic effects in the human...
5.
Gruden E, Kienzl M, Ristic D, Kindler O, Kaspret D, Schmid S, et al.
Front Immunol
. 2024 Feb;
15:1347259.
PMID: 38318168
Introduction: Eosinophilic esophagitis (EoE) is a chronic, inflammatory, antigen-driven disease of the esophagus. Tissue EoE pathology has previously been extensively characterized by novel transcriptomics and proteomic platforms, however the majority...
6.
Kienzl M, Maitz K, Sarsembayeva A, Valadez-Cosmes P, Gruden E, Ristic D, et al.
Cancers (Basel)
. 2024 Jan;
16(2).
PMID: 38254785
The tumor microenvironment (TME) is pivotal in cancer progression and the response to immunotherapy. A "hot" tumor typically contains immune cells that promote anti-tumor immunity, predicting positive prognosis. "Cold" tumors...
7.
Maitz K, Valadez-Cosmes P, Raftopoulou S, Kindler O, Kienzl M, Bolouri H, et al.
Cancers (Basel)
. 2023 Dec;
15(24.
PMID: 38136314
Lung cancer is the leading cause of cancer-related death worldwide. Discoidin domain receptor 1 (DDR1), a tyrosine kinase receptor, has been associated with poor prognosis in patients with non-small cell...
8.
Stadler J, Habisch H, Pruller F, Mangge H, Barnthaler T, Kargl J, et al.
Antioxidants (Basel)
. 2023 Nov;
12(11).
PMID: 38001862
COVID-19, caused by the SARS-CoV-2 coronavirus, emerged as a global pandemic in late 2019, resulting in significant global public health challenges. The emerging evidence suggests that diminished high-density lipoprotein (HDL)...
9.
Cosic-Mujkanovic N, Valadez-Cosmes P, Maitz K, Lueger A, Mihalic Z, Runtsch M, et al.
Antioxidants (Basel)
. 2023 Aug;
12(8).
PMID: 37627581
Myeloperoxidase (MPO) is a neutrophil-derived enzyme that has been recently associated with tumour development. However, the mechanisms by which this enzyme exerts its functions remain unclear. In this study, we...
10.
Gruden E, Kienzl M, Hasenoehrl C, Sarsembayeva A, Ristic D, Schmid S, et al.
Prostaglandins Leukot Essent Fatty Acids
. 2023 Aug;
196():102585.
PMID: 37573716
We recently described that monoacylglycerol lipase (MGL) is present in the tumor microenvironment (TME), increasing tumor growth. In this study we compare the implications of MGL deficiency in the TME...