Julia Kapr
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Explore the profile of Julia Kapr including associated specialties, affiliations and a list of published articles.
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9
Citations
78
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Recent Articles
1.
Lislien M, Kuchovska E, Kapr J, Duale N, Andersen J, Dirven H, et al.
Toxicology
. 2024 Nov;
510:154000.
PMID: 39551125
The safety and developmental neurotoxicity (DNT) potential of chemicals remain critically understudied due to limitations of current in vivo testing guidelines, which are low throughput, resource-intensive, and hindered by species...
2.
Kapr J, Scharkin I, Ramachandran H, Westhoff P, Pollet M, Dangeleit S, et al.
Cell Mol Life Sci
. 2024 Aug;
81(1):368.
PMID: 39179905
Cockayne Syndrome B (CSB) is a hereditary multiorgan syndrome which-through largely unknown mechanisms-can affect the brain where it clinically presents with microcephaly, intellectual disability and demyelination. Using human induced pluripotent...
3.
Szepanowski L, Wruck W, Kapr J, Rossi A, Fritsche E, Krutmann J, et al.
Cells
. 2024 Apr;
13(7.
PMID: 38607030
Cockayne syndrome (CS) is a rare hereditary autosomal recessive disorder primarily caused by mutations in Cockayne syndrome protein A (CSA) or B (CSB). While many of the functions of CSB...
4.
Koch K, Bartmann K, Hartmann J, Kapr J, Klose J, Kuchovska E, et al.
Front Toxicol
. 2022 Mar;
4:816370.
PMID: 35295221
There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current guideline studies. Under...
5.
Kapr J, Petersilie L, Distler T, Lauria I, Bendt F, Sauter C, et al.
Adv Healthc Mater
. 2021 Jul;
10(16):e2100131.
PMID: 34197049
Stable and predictive neural cell culture models are a necessary premise for many research fields. However, conventional 2D models lack 3D cell-material/-cell interactions and hence do not reflect the complexity...
6.
Tigges J, Bielec K, Brockerhoff G, Hildebrandt B, Hubenthal U, Kapr J, et al.
ALTEX
. 2021 May;
38(4):595-614.
PMID: 33963415
Human induced pluripotent stem cells (hiPSC) are a promising tool for replacing animal-based experiments. To warrant data reproducibility, quality-controlled research material is recommended. While the need for global harmonization of...
7.
Distler T, Lauria I, Detsch R, Sauter C, Bendt F, Kapr J, et al.
Biomedicines
. 2021 Apr;
9(3).
PMID: 33808044
Biodegradable hydrogels that promote stem cell differentiation into neurons in three dimensions (3D) are highly desired in biomedical research to study drug neurotoxicity or to yield cell-containing biomaterials for neuronal...
8.
Fritsche E, Haarmann-Stemmann T, Kapr J, Galanjuk S, Hartmann J, Mertens P, et al.
Small
. 2020 Dec;
17(15):e2006252.
PMID: 33354870
The call for a paradigm change in toxicology from the United States National Research Council in 2007 initiates awareness for the invention and use of human-relevant alternative methods for toxicological...
9.
Fritsche E, Tigges J, Hartmann J, Kapr J, Serafini M, Viviani B
Handb Exp Pharmacol
. 2020 Jun;
265:111-141.
PMID: 32594299
Animal models have been greatly contributing to our understanding of physiology, mechanisms of diseases, and toxicity. Yet, their limitations due to, e.g., interspecies variation are reflected in the high number...