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Julia E Rood

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Articles 13
Citations 670
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Recent Articles
1.
Rood J, Rezk A, Pogoriler J, Finn L, Burnham J, Josephson M, et al.
J Clin Immunol . 2022 Aug; 43(1):101-108. PMID: 36006569
Systemic juvenile idiopathic arthritis associated with interstitial lung disease (SJIA-LD) represents a highly morbid subset of SJIA for which effective therapies are lacking. We report the case of a patient...
2.
Rood J, Behrens E
Annu Rev Pathol . 2021 Oct; 17:227-249. PMID: 34699263
Autoinflammation describes a collection of diverse diseases caused by indiscriminate activation of the immune system in an antigen-independent manner. The rapid advancement of genetic diagnostics has allowed for the identification...
3.
Isenberg S, Carter M, Moon J, Laughlin S, Petway M, Mojica M, et al.
J Appl Lab Med . 2020 May; 5(2):273-280. PMID: 32445395
Background: Irradiative sterilization of clinical specimens prior to chemical laboratory testing provides a way to not only sterilize pathogens and ensure laboratorian safety but also preserve sample volume and maintain...
4.
Flynn R, Hill M, Rood J, Parga J
Clin Pediatr (Phila) . 2020 Jan; 59(4-5):532-535. PMID: 31971002
No abstract available.
5.
Burn T, Weaver L, Rood J, Chu N, Bodansky A, Kreiger P, et al.
Arthritis Rheumatol . 2019 Aug; 72(2):335-347. PMID: 31400073
Objective: Familial hemophagocytic lymphohistiocytosis (FHLH) is a complex cytokine storm syndrome caused by genetic abnormalities rendering CD8+ T cells and natural killer cells incapable of cytolytic killing. In murine models...
6.
Rood J, Burn T, Neal V, Chu N, Behrens E
Front Immunol . 2018 Dec; 9:2642. PMID: 30515155
Danger signals mediated through ST2, the interleukin-33 (IL-33) receptor, amplify CD8 T cell-mediated inflammation in the murine model of familial hemophagocytic lymphohistiocytosis type 2 (FHL2), and blockade of ST2 provides...
7.
Avetisyan M, Rood J, Lopez S, Sengupta R, Wright-Jin E, Dougherty J, et al.
Proc Natl Acad Sci U S A . 2018 Apr; 115(18):4696-4701. PMID: 29666241
The nervous system of the bowel regulates the inflammatory phenotype of tissue resident muscularis macrophages (MM), and in adult mice, enteric neurons are the main local source of colony stimulating...
8.
Rood J, Canna S, Weaver L, Tobias J, Behrens E
J Leukoc Biol . 2016 Dec; 101(4):1037-1044. PMID: 28034913
Immune-mediated liver injury is a central feature of hyperinflammatory diseases, such as hemophagocytic syndromes, yet the immunologic mechanisms underlying those processes are incompletely understood. In this study, we used the...
9.
Rood J, Rao S, Paessler M, Kreiger P, Chu N, Stelekati E, et al.
Blood . 2015 Nov; 127(4):426-35. PMID: 26518437
Cytokine storm syndromes, such as familial hemophagocytic lymphohistiocytosis (FHL), are lethal disorders caused by uncontrolled, systemic immune activation. In the murine model of FHL, in which perforin-deficient (Prf1(-/-)) mice are...
10.
Mendoza D, Migueles S, Rood J, Peterson B, Johnson S, Doria-Rose N, et al.
PLoS Pathog . 2013 Mar; 9(2):e1003195. PMID: 23468632
Although the study of non-human primates has resulted in important advances for understanding HIV-specific immunity, a clear correlate of immune control over simian immunodeficiency virus (SIV) replication has not been...