Claire W Hallahan
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Explore the profile of Claire W Hallahan including associated specialties, affiliations and a list of published articles.
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43
Citations
3336
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Recent Articles
1.
Migueles S, Nettere D, Gavil N, Wang L, Toulmin S, Kelly E, et al.
Science
. 2023 Dec;
382(6676):1270-1276.
PMID: 38096385
Current HIV vaccines designed to stimulate CD8 T cells have failed to induce immunologic control upon infection. The functions of vaccine-induced HIV-specific CD8 T cells were investigated here in detail....
2.
Migueles S, Mendoza D, Zimmerman M, Martins K, Toulmin S, Kelly E, et al.
EBioMedicine
. 2015 Jul;
2(1):46-58.
PMID: 26137533
Understanding natural immunologic control over Human Immunodeficiency Virus (HIV)-1 replication, as occurs in rare long-term nonprogressors/elite controllers (LTNP/EC), should inform the design of efficacious HIV vaccines and immunotherapies. Durable control...
3.
Chun T, Murray D, Justement J, Blazkova J, Hallahan C, Fankuchen O, et al.
Proc Natl Acad Sci U S A
. 2014 Aug;
111(36):13151-6.
PMID: 25157148
Several highly potent and broadly neutralizing monoclonal antibodies against HIV have recently been isolated from B cells of infected individuals. However, the effects of these antibodies on the persistent viral...
4.
Chun T, Justement J, Murray D, Kim C, Blazkova J, Hallahan C, et al.
J Infect Dis
. 2013 Jul;
208(9):1443-7.
PMID: 23847057
Elite controllers suppress human immunodeficiency virus (HIV) viremia to below the limit of detection in the absence of antiretroviral therapy (ART). However, precise frequencies of CD4(+) T cells carrying replication-competent...
5.
Mendoza D, Migueles S, Rood J, Peterson B, Johnson S, Doria-Rose N, et al.
PLoS Pathog
. 2013 Mar;
9(2):e1003195.
PMID: 23468632
Although the study of non-human primates has resulted in important advances for understanding HIV-specific immunity, a clear correlate of immune control over simian immunodeficiency virus (SIV) replication has not been...
6.
Blazkova J, Chun T, Belay B, Murray D, Justement J, Funk E, et al.
J Infect Dis
. 2012 Jun;
206(5):765-9.
PMID: 22732922
Persistence of the latent viral reservoir has been recognized as a major obstacle to eradicating human immunodeficiency virus (HIV) in infected individuals receiving antiretroviral therapy. It has been suggested that...
7.
Smalls-Mantey A, Doria-Rose N, Klein R, Patamawenu A, Migueles S, Ko S, et al.
J Virol
. 2012 Jun;
86(16):8672-80.
PMID: 22674985
Antibody (Ab)-dependent cellular cytotoxicity (ADCC) is thought to potentially play a role in vaccine-induced protection from HIV-1. The characteristics of such antibodies remain incompletely understood. Furthermore, correlates between ADCC and...
8.
Mendoza D, Johnson S, Peterson B, Natarajan V, Salgado M, Dewar R, et al.
Blood
. 2012 Apr;
119(20):4645-55.
PMID: 22490332
True long-term nonprogressors (LTNPs)/elite controllers (ECs) maintain durable control over HIV replication without antiretroviral therapy. Herein we describe 4 unique persons who were distinct from conventional LTNPs/ECs in that they...
9.
Chun T, Murray D, Justement J, Hallahan C, Moir S, Kovacs C, et al.
J Infect Dis
. 2011 Jun;
204(1):135-8.
PMID: 21628667
Residual plasma viremia (<50 copies/mL) persists in certain human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART); however, the relationship between the degree of residual plasma viremia, the size of...
10.
Migueles S, Rood J, Berkley A, Guo T, Mendoza D, Patamawenu A, et al.
PLoS Pathog
. 2011 Mar;
7(2):e1002002.
PMID: 21383976
If future HIV vaccine design strategies are to succeed, improved understanding of the mechanisms underlying protection from infection or immune control over HIV replication remains essential. Increased cytotoxic capacity of...