Julia E Babensee
Overview
Explore the profile of Julia E Babensee including associated specialties, affiliations and a list of published articles.
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38
Citations
754
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Recent Articles
1.
Bulondo F, Babensee J
J Biomed Mater Res A
. 2024 Apr;
112(8):1317-1336.
PMID: 38562052
Translational research in biomaterials and immunoengineering is leading to the development of novel advanced therapeutics to treat diseases such as cancer, autoimmunity, and viral infections. Dendritic cells (DCs) are at...
2.
Beskid N, Kolawole E, Coronel M, Nguyen B, Evavold B, Garcia A, et al.
ACS Biomater Sci Eng
. 2022 Sep;
8(10):4341-4353.
PMID: 36134725
Biomaterial systems such as hydrogels enable localized delivery and postinjection modulation of cellular therapies in a wide array of contexts. Biomaterials as adjuvants have been an active area of investigation,...
3.
Srinivasan S, Babensee J
ACS Biomater Sci Eng
. 2021 Jan;
6(7):4062-4076.
PMID: 33463332
Engineering a regulatory phenotype in dendritic cells (DCs) is a potential approach to circumvent an immune response against self-antigens in autoimmunity or alloantigens in allograft rejection. Cell microenvironments influence the...
4.
Thomas A, Beskid N, Blanchfield J, Rosado A, Garcia A, Evavold B, et al.
J Biomed Mater Res A
. 2020 Oct;
109(7):1247-1255.
PMID: 33040412
In multiple sclerosis (MS), abnormally activated immune cells responsive to myelin proteins result in widespread damage throughout the central nervous system (CNS) and ultimately irreversible disability. Immunomodulation by delivering dendritic...
5.
Thomas A, Dong Y, Beskid N, Garcia A, Adams A, Babensee J
J Cell Physiol
. 2019 Nov;
235(6):5120-5129.
PMID: 31674663
Dendritic cells are key players in regulating immunity. These cells both activate and inhibit the immune response depending on their cellular environment. Their response to hyperglycemia, a condition common amongst...
6.
Hotaling N, Tang L, Irvine D, Babensee J
Annu Rev Biomed Eng
. 2015 Oct;
17:317-49.
PMID: 26421896
Strategies to enhance, suppress, or qualitatively shape the immune response are of importance for diverse biomedical applications, such as the development of new vaccines, treatments for autoimmune diseases and allergies,...
7.
Hotaling N, Cummings R, Ratner D, Babensee J
Biomaterials
. 2014 Apr;
35(22):5862-74.
PMID: 24746228
Carbohydrates and glycoconjugates have been shown to exert pro-inflammatory effects on the dendritic cells (DCs), supporting pathogen-induced innate immunity and antigen processing, as well as immunosuppressive effects in the tolerance...
8.
Park J, Gerber M, Babensee J
J Biomed Mater Res A
. 2014 Mar;
103(1):170-84.
PMID: 24616366
Given the central role of dendritic cells (DCs) in directing T-cell phenotypes, the ability of biomaterial-treated DCs to dictate autologous T-cell phenotype was investigated. In this study, we demonstrate that...
9.
Park J, Babensee J
Acta Biomater
. 2012 Jun;
8(10):3606-17.
PMID: 22705044
The immunological outcome of dendritic cell (DC) treatment with different biomaterials was assessed to demonstrate the range of DC phenotypes induced by biomaterials commonly used in combination products. Immature DCs...
10.
Kou P, Pallassana N, Bowden R, Cunningham B, Joy A, Kohn J, et al.
Biomaterials
. 2011 Dec;
33(6):1699-713.
PMID: 22136715
Dendritic cells (DCs) play a critical role in orchestrating the host responses to a wide variety of foreign antigens and are essential in maintaining immune tolerance. Distinct biomaterials have been...