Judy Tellam
Overview
Explore the profile of Judy Tellam including associated specialties, affiliations and a list of published articles.
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22
Citations
901
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Recent Articles
1.
Murat P, Tellam J
Wiley Interdiscip Rev RNA
. 2014 Sep;
6(2):157-71.
PMID: 25264139
Effective T-cell surveillance of antigen-presenting cells is dependent on the expression of an array of antigenic peptides bound to major histocompatibility complex (MHC) class I (MHC-I) or class II (MHC-II)...
2.
Murat P, Zhong J, Lekieffre L, Cowieson N, Clancy J, Preiss T, et al.
Nat Chem Biol
. 2014 Mar;
10(5):358-64.
PMID: 24633353
Viruses that establish latent infections have evolved unique mechanisms to avoid host immune recognition. Maintenance proteins of these viruses regulate their synthesis to levels sufficient for maintaining persistent infection but...
3.
Smith C, Elhassen D, Gras S, Wynn K, Dasari V, Tellam J, et al.
Blood
. 2012 Sep;
120(16):3237-45.
PMID: 22942184
T-box transcription factors T-bet (Tbx21) and Eomesodermin (Eomes) are critical players in CD8(+) cytotoxic T lymphocyte effector function and differentiation, but how the expression of these transcription factors is regulated...
4.
Sun X, Barlow E, Ma S, Hagemeier S, Duellman S, Burgess R, et al.
Proc Natl Acad Sci U S A
. 2010 Feb;
107(7):3146-51.
PMID: 20133771
EBV causes infectious mononucleosis and is associated with certain malignancies. EBV nuclear antigen 1 (EBNA1) mediates EBV genome replication, partition, and transcription, and is essential for persistence of the viral...
5.
Bell M, Burrows J, Brennan R, Miles J, Tellam J, McCluskey J, et al.
Mol Immunol
. 2009 Jan;
46(8-9):1911-7.
PMID: 19157553
The major ligands presented by MHC class I molecules after natural antigen processing are peptides of eight to ten residues in length, and it is widely accepted that the binding...
6.
Ressing M, Horst D, Griffin B, Tellam J, Zuo J, Khanna R, et al.
Semin Cancer Biol
. 2008 Nov;
18(6):397-408.
PMID: 18977445
Upon primary infection, EBV establishes a latent infection in B cells, characterized by maintenance of the viral genome in the absence of viral replication. The Epstein-Barr Nuclear Antigen 1 (EBNA1)...
7.
Webb N, Connolly G, Tellam J, Yap A, Khanna R
PLoS One
. 2008 Sep;
3(9):e3254.
PMID: 18806872
Previous studies have indicated that Epstein-Barr virus (EBV) can modulate the Wnt pathway in virus-infected cells and this effect is mediated by EBV-encoded oncogene latent membrane protein 1 (LMP1). Here...
8.
Tellam J, Smith C, Rist M, Webb N, Cooper L, Vuocolo T, et al.
Proc Natl Acad Sci U S A
. 2008 Jul;
105(27):9319-24.
PMID: 18591662
Many viruses avoid immune surveillance during latent infection through reduction in the synthesis of virally encoded proteins. Although antigen presentation critically depends on the level of viral protein synthesis, the...
9.
Tellam J, Fogg M, Rist M, Connolly G, Tscharke D, Webb N, et al.
J Exp Med
. 2007 Feb;
204(3):525-32.
PMID: 17312009
A significant proportion of endogenously processed CD8(+) T cell epitopes are derived from newly synthesized proteins and rapidly degrading polypeptides (RDPs). It has been hypothesized that the generation of rapidly...
10.
Tellam J, Rist M, Connolly G, Webb N, Fazou C, Wang F, et al.
Eur J Immunol
. 2007 Jan;
37(2):328-37.
PMID: 17236233
Lymphocryptoviruses (LCV) that infect humans and Old World primates display a significant degree of genetic identity. These viruses use B lymphocytes as primary host cells to establish a long-term latent...