Judith C W Mak
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Explore the profile of Judith C W Mak including associated specialties, affiliations and a list of published articles.
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49
Citations
764
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Recent Articles
1.
Feng X, Ye Y, Zhang J, Zhang Y, Zhao S, Mak J, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(18):e2310283121.
PMID: 38669183
Congenital scoliosis (CS), affecting approximately 0.5 to 1 in 1,000 live births, is commonly caused by congenital vertebral malformations (CVMs) arising from aberrant somitogenesis or somite differentiation. While Wnt/ß-catenin signaling...
2.
Tong X, Gao L, Wong I, Chan V, Wong A, Mak J, et al.
Int J Epidemiol
. 2024 Feb;
53(1).
PMID: 38332579
Background: Recommendations around the use of 23-valent pneumococcal polysaccharide vaccine (PPSV23) and 13-valent pneumococcal conjugate vaccine (PCV13) seldom focus on potential benefits of vaccine on comorbidities. We aimed to investigate...
3.
Chen R, Cui Y, Mak J
Adv Pharmacol
. 2023 Jul;
98:225-247.
PMID: 37524488
Chronic obstructive pulmonary disease (COPD) is a major cause of death and reduces quality of life that contributes to a health problem worldwide. Chronic airway inflammation is a hallmark of...
4.
Garcia J, Rogers A, Mak J, Halayko A, Hui C, Xu B, et al.
Am J Respir Cell Mol Biol
. 2022 Jun;
67(4):471-481.
PMID: 35763375
Mitochondrial dysfunction has been reported in chronic obstructive pulmonary disease (COPD). Transfer of mitochondria from mesenchymal stem cells to airway smooth muscle cells (ASMCs) can attenuate oxidative stress-induced mitochondrial damage....
5.
Ji Y, Liang Y, Mak J, Ip M
Sleep Med
. 2022 May;
95:16-28.
PMID: 35537279
With the current epidemic of obesity worldwide, the prevalence of various obesity-related diseases is constantly increasing. Obesity remains the strongest phenotypic risk factor in both obstructive sleep apnea (OSA) and...
6.
Chen R, Michaeloudes C, Liang Y, Bhavsar P, Chung K, Ip M, et al.
J Allergy Clin Immunol
. 2021 Oct;
149(4):1445-1457.e5.
PMID: 34624393
Background: Orosomucoid 1-like protein 3 (ORMDL3), a transmembrane protein localized in the endoplasmic reticulum (ER), has been genetically associated with chronic obstructive pulmonary disease (COPD), in addition to childhood-onset asthma....
7.
Michaeloudes C, Li X, Mak J, Bhavsar P
Methods Mol Biol
. 2021 Mar;
2269:93-105.
PMID: 33687674
Mesenchymal stem cells (MSCs) have emerged as an attractive candidate for cell-based therapy. In the past decade, many animal and pilot clinical studies have demonstrated that MSCs are therapeutically beneficial...
8.
Cui Y, Liu K, Ip M, Liang Y, Mak J
Ann Transl Med
. 2020 Dec;
8(21):1418.
PMID: 33313163
Background: Cigarette smoke (CS)-induced build-up of oxidative stress is the leading cause of chronic obstructive pulmonary disease (COPD). Monoamine oxidases (MAOs) are novel sources of reactive oxygen species (ROS) due...
9.
Cui Y, Liang Y, Ip M, Mak J
Life Sci
. 2020 Dec;
265:118862.
PMID: 33301812
Aims: The 18 kDa translocator protein (TSPO) - also known as peripheral benzodiazepine receptor, is found to be expressed in lung epithelium and pneumocytes, which is closely associated with the...
10.
Liang Y, Mak J
Curr Pharm Des
. 2020 Nov;
27(12):1469-1481.
PMID: 33243107
Asthma and chronic obstructive pulmonary disease (COPD) are obstructive lung diseases which are characterized by chronic inflammation and an increase in mucus production, and are highly prevalent conditions. Despite recent...