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Judith Bockstiegel

Explore the profile of Judith Bockstiegel including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 17
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Recent Articles
1.
Bockstiegel J, Engelhardt J, Schuchardt M, Tolle M, Weindl G
Mol Med . 2025 Feb; 31(1):72. PMID: 39984847
Background: The endogenous nucleotide adenosine 5'-tetraphosphate (Ap4) is a potent vasoconstrictor. Despite its structural similarity to the danger signal adenosine 5'-triphosphate (ATP), the immunomodulatory effects of Ap4 remain unclear. Methods:...
2.
Bockstiegel J, Engelhardt J, Weindl G
Cell Commun Signal . 2023 Nov; 21(1):335. PMID: 37996864
Background: The purinergic receptor P2X7 plays a crucial role in infection, inflammation, and cell death. It is thought that P2X7 receptor stimulation triggers processing and release of the pro-inflammatory cytokine...
3.
Bockstiegel J, Wurnig S, Engelhardt J, Enns J, Hansen F, Weindl G
Biochem Pharmacol . 2023 Jul; 215:115693. PMID: 37481141
The nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome is an important regulator of inflammation and immune responses. Histone deacetylase 6 (HDAC6) has been implicated in the...
4.
Lubow C, Bockstiegel J, Weindl G
Biochem Pharmacol . 2020 Feb; 175:113864. PMID: 32088265
Interleukin (IL)-1 signaling leads to production of pro-inflammatory mediators and is regulated by receptor endocytosis. Lysosomotropic drugs have been linked to increased pro-inflammatory responses under sterile inflammatory conditions but the...