Judith A Mack
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Explore the profile of Judith A Mack including associated specialties, affiliations and a list of published articles.
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20
Citations
362
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Recent Articles
1.
Maytin E, Zeitouni N, Updyke A, Negrey J, Shen A, Heusinkveld L, et al.
medRxiv
. 2025 Feb;
PMID: 39974008
Photodynamic therapy (PDT) with topical aminolevulinic acid (ALA) can be effective for select basal cell carcinoma (BCC) lesions. However, the histological depth and subtype of tumors that respond to PDT...
2.
Bullock T, Mack J, Negrey J, Kaw U, Hu B, Anand S, et al.
J Invest Dermatol
. 2023 Feb;
143(8):1538-1547.
PMID: 36813159
Vitamin D3, a prohormone, is converted to circulating calcidiol and then to calcitriol, the hormone that binds to the vitamin D receptor (VDR) (a nuclear transcription factor). Polymorphic genetic sequence...
3.
Wang Y, Mack J, Hascall V, Maytin E
Am J Pathol
. 2022 Sep;
192(12):1683-1698.
PMID: 36063901
Normal myofibroblast differentiation is critical for proper skin wound healing. Neoexpression of α-smooth muscle actin (α-SMA), a marker for myofibroblast differentiation, is driven by transforming growth factor (TGF)-β receptor-mediated signaling....
4.
Shakya S, Asosingh K, Mack J, Maytin E
MethodsX
. 2020 Sep;
7:101027.
PMID: 32939347
The incidence of chronic, non-healing skin wounds is accelerating, largely due to the epidemic of obesity-related Type 2 diabetes. Abnormal inflammation in wounds contributes to delayed healing. During wound repair,...
5.
Cutaneous Wounds in Mice Lacking TSG-6 Exhibit Delayed Closure and an Abnormal Inflammatory Response
Shakya S, Mack J, Alipour M, Maytin E
J Invest Dermatol
. 2020 May;
140(12):2505-2514.
PMID: 32422216
We investigated how loss of TSG-6 affects wound closure and skin inflammation. TSG-6 has several known biological functions, including the enzymatic transfer of heavy-chain proteins from inter-α-trypsin inhibitor to hyaluronan...
6.
Wang Y, Mack J, Maytin E
J Biol Chem
. 2019 Jul;
294(34):12779-12794.
PMID: 31285260
Well-regulated differentiation of fibroblasts into myofibroblasts (MF) is critical for skin wound healing. Neoexpression of α-smooth muscle actin (α-SMA), an established marker for MF differentiation, is driven by TGFβ receptor...
7.
Maytin E, Kaw U, Ilyas M, Mack J, Hu B
Photodiagnosis Photodyn Ther
. 2018 Feb;
22:7-13.
PMID: 29471147
Background: Photodynamic therapy (PDT) is a non-scarring alternative for treating basal cell carcinoma (BCC) in patients with Basal Cell Nevus Syndrome (BCNS), also known as Gorlin syndrome. In Europe, red...
8.
Ghatak S, Maytin E, Mack J, Hascall V, Atanelishvili I, Moreno Rodriguez R, et al.
Int J Cell Biol
. 2015 Oct;
2015:834893.
PMID: 26448760
A wound is a type of injury that damages living tissues. In this review, we will be referring mainly to healing responses in the organs including skin and the lungs....
9.
Shakya S, Wang Y, Mack J, Maytin E
Int J Cell Biol
. 2015 Oct;
2015:701738.
PMID: 26448756
Ulcers and chronic wounds are a particularly common problem in diabetics and are associated with hyperglycemia. In this targeted review, we summarize evidence suggesting that defective wound healing in diabetics...
10.
Wang Y, Lauer M, Anand S, Mack J, Maytin E
J Biol Chem
. 2014 Oct;
289(46):32253-32265.
PMID: 25266724
A balanced turnover of dermal fibroblasts is crucial for structural integrity and normal function of the skin. During recovery from environmental injury (such as UV exposure and physical wounding), apoptosis...