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Juan S Gnecco

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Citations 353
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Recent Articles
1.
Gnecco J, Brown A, Buttrey K, Ives C, Goods B, Baugh L, et al.
Med . 2023 Aug; 4(8):554-579.e9. PMID: 37572651
Background: The human endometrium undergoes recurring cycles of growth, differentiation, and breakdown in response to sex hormones. Dysregulation of epithelial-stromal communication during hormone-mediated signaling may be linked to myriad gynecological...
2.
Gnecco J, Brown A, Kan E, Baugh L, Ives C, Loring M, et al.
Semin Reprod Med . 2020 Nov; 38(2-03):179-196. PMID: 33176387
Adenomyosis remains an enigmatic disease in the clinical and research communities. The high prevalence, diversity of morphological and symptomatic presentations, array of potential etiological explanations, and variable response to existing...
3.
Hernandez-Gordillo V, Kassis T, Lampejo A, Choi G, Gamboa M, Gnecco J, et al.
Biomaterials . 2020 Jun; 254:120125. PMID: 32502894
Epithelial organoids derived from human donor tissues are important tools in fields ranging from regenerative medicine to drug discovery. Organoid culture requires expansion of stem/progenitor cells in Matrigel, a tumor-derived...
4.
Gnecco J, Ding T, Smith C, Lu J, Bruner-Tran K, Osteen K
Hum Reprod . 2019 Feb; 34(4):702-714. PMID: 30789661
Study Question: Does the uterine vasculature play a localized role in promoting stromal cell decidualization in the human endometrium? Summary Answer: Our study demonstrated that hemodynamic forces induced secretion of...
5.
Rogers L, Anders A, Doster R, Gill E, Gnecco J, Holley J, et al.
Am J Reprod Immunol . 2018 Aug; 80(4):e13032. PMID: 30084522
Problem: Bacterial chorioamnionitis causes adverse pregnancy outcomes, yet host-microbial interactions are not well characterized within gestational membranes. The decidua, the outermost region of the membranes, is a potential point of...
6.
Loperena R, Van Beusecum J, Itani H, Engel N, Laroumanie F, Xiao L, et al.
Cardiovasc Res . 2018 May; 114(11):1547-1563. PMID: 29800237
Aims: Monocytes play an important role in hypertension. Circulating monocytes in humans exist as classical, intermediate, and non-classical forms. Monocyte differentiation can be influenced by the endothelium, which in turn...
7.
Alexander M, Norlander A, Elijovich F, Atreya R, Gaye A, Gnecco J, et al.
Br J Pharmacol . 2018 May; 176(12):2015-2027. PMID: 29774543
Background And Purpose: Monocytes play a critical role in hypertension. The purpose of our study was to use an unbiased approach to determine whether hypertensive individuals on conventional therapy exhibit...
8.
Gnecco J, Anders A, Cliffel D, Pensabene V, Rogers L, Osteen K, et al.
Curr Pharm Des . 2017 Aug; 23(40):6115-6124. PMID: 28847303
Preterm birth (PTB) is clinically defined as process of giving birth before 37 weeks of gestation and is a leading cause of death among neonates and children under the age...
9.
Gnecco J, Pensabene V, Li D, Ding T, Hui E, Bruner-Tran K, et al.
Ann Biomed Eng . 2017 Jan; 45(7):1758-1769. PMID: 28108942
The endometrium is the inner lining of the uterus. Following specific cyclic hormonal stimulation, endometrial stromal fibroblasts (stroma) and vascular endothelial cells exhibit morphological and biochemical changes to support embryo...
10.
Pensabene V, Costa L, Terekhov A, Gnecco J, Wikswo J, Hofmeister W
ACS Appl Mater Interfaces . 2016 Aug; 8(34):22629-36. PMID: 27513606
The basal lamina or basement membrane (BM) is a key physiological system that participates in physicochemical signaling between tissue types. Its formation and function are essential in tissue maintenance, growth,...