Juan Pablo Huidobro-Toro
Overview
Explore the profile of Juan Pablo Huidobro-Toro including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
267
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Recent Articles
1.
Leiva-Salcedo E, Riquelme D, Huidobro-Toro J, Coddou C
Pharmaceuticals (Basel)
. 2025 Jan;
17(12.
PMID: 39770432
P2X receptor channels are widely expressed in the CNS, where they have multiple functions in health and disease. The rat P2X2a (rP2X2a) receptor channel is modulated by copper, an essential...
2.
Acuna-Castillo C, Escobar A, Garcia-Gomez M, Bachelet V, Huidobro-Toro J, Sauma D, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38473744
The P2X7 receptor, a member of the P2X purinergic receptor family, is a non-selective ion channel. Over the years, it has been associated with various biological functions, from modulating to...
3.
Mascayano C, Munoz-Osses M, Navarrete E, Torres P, Torres-Gonzalez S, Morales P, et al.
J Biomol Struct Dyn
. 2023 Nov;
42(24):13529-13537.
PMID: 37909479
This study explored new methods to inhibit human 5-lipoxygenase (5-hLOX) by analyzing natural terpenes that share structural similarities with acetoxyboswellic acid (AKBA). Enzymatic assays were used to evaluate the terpene's...
4.
Barrera-Avalos C, Briceno P, Valdes D, Imarai M, Leiva-Salcedo E, Rojo L, et al.
iScience
. 2021 Dec;
24(12):103520.
PMID: 34950860
T cell activation requires the processing and presentation of antigenic peptides in the context of a major histocompatibility complex (MHC complex). Cross-dressing is a non-conventional antigen presentation mechanism, involving the...
5.
Robles-Planells C, Barrera-Avalos C, Rojo L, Spencer E, Cortez-San Martin M, Matiacevich S, et al.
Biomed Res Int
. 2020 Jul;
2020:4045760.
PMID: 32626742
Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of...
6.
Robles-Planells C, Sanchez-Guerrero G, Barrera-Avalos C, Matiacevich S, Rojo L, Pavez J, et al.
Mediators Inflamm
. 2020 May;
2020:8680692.
PMID: 32410869
Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation and immunogenic...
7.
Calfio C, Huidobro-Toro J
Molecules
. 2019 Jul;
24(15).
PMID: 31349544
Hydroalcoholic extracts of Patagonian Calafate berry () contain mono or disaccharide conjugated anthocyanins and flavonols. The Liquid Chromatography-Mass Spectrometry (LC-MS) chemical extract profile identified glycosylated anthocyanidins such as delphinidin-, petunidin-...
8.
Diaz-Saldivar P, Huidobro-Toro J
Int J Nanomedicine
. 2019 May;
14:2433-2447.
PMID: 31040666
Purpose: The antitumoral effect of ATP requires its accumulation in the extracellular space to interact with membrane receptors in target cells. We propose the use of albumin nanoparticles (ANPs) coated...
9.
Rodriguez F, Laporte D, Gonzalez A, Mendez K, Castro-Nallar E, Meneses C, et al.
BMC Genomics
. 2018 Nov;
19(1):829.
PMID: 30458726
Background: The marine alga Ulva compressa is the dominant species in coastal areas receiving effluents from copper mines. The alga can accumulate high amounts of copper and possesses a strong...
10.
Peralta F, Huidobro-Toro J
Int J Mol Sci
. 2016 Jul;
17(7).
PMID: 27384555
Zinc is an essential metal to life. This transition metal is a structural component of many proteins and is actively involved in the catalytic activity of cell enzymes. In either...