Juan P Ianowski
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Explore the profile of Juan P Ianowski including associated specialties, affiliations and a list of published articles.
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29
Citations
327
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Recent Articles
1.
Luan X, Henao Romero N, Campanucci V, Le Y, Mustofa J, Tam J, et al.
Am J Respir Crit Care Med
. 2024 Apr;
210(6):788-800.
PMID: 38573173
Pulmonary ionocytes are a newly discovered airway epithelial cell type proposed to be a major contributor to cystic fibrosis (CF) lung disease based on observations they express the cystic fibrosis...
2.
Hassan N, Murray B, Jagadeeshan S, Thomas R, Katselis G, Ianowski J
iScience
. 2024 Jan;
27(1):108629.
PMID: 38188522
Since the early seminal studies on epithelial solute transport, it has been understood that there must be crosstalk among different members of the transport machinery to coordinate their activity and,...
3.
Luan X, Le Y, Jagadeeshan S, Murray B, Carmalt J, Duke T, et al.
Cell Rep
. 2021 Oct;
37(1):109795.
PMID: 34610318
A controversial hypothesis pertaining to cystic fibrosis (CF) lung disease is that the CF transmembrane conductance regulator (CFTR) channel fails to inhibit the epithelial Na channel (ENaC), yielding increased Na...
4.
Capriotti N, Gioino P, Ons S, Ianowski J
J Exp Biol
. 2021 May;
224(10).
PMID: 34008838
Rhodnius prolixus is a blood-feeding insect vector of Trypanosoma cruzi, a protozoan parasite that causes Chagas disease. During each blood meal, the animals ingest large volumes of blood, that may...
5.
Nair M, Jagadeeshan S, Katselis G, Luan X, Momeni Z, Henao-Romero N, et al.
Sci Rep
. 2021 Apr;
11(1):8336.
PMID: 33863932
Thoracic dorsal root ganglia (tDRG) contribute to fluid secretion in the upper airways. Inflammation potentiates DRG responses, but the mechanisms remain under investigation. The receptor for advanced glycation end-products (RAGE)...
6.
Kim D, Liao J, Scales N, Martini C, Luan X, Abu-Arish A, et al.
J Exp Med
. 2021 Feb;
218(4).
PMID: 33533914
The airway mucosal microenvironment is crucial for host defense against inhaled pathogens but remains poorly understood. We report here that the airway surface normally undergoes surprisingly large excursions in pH...
7.
Luan X, Tam J, Jagadeeshan S, Grishchenko N, Hassan N, Gioino P, et al.
Am J Physiol Lung Cell Mol Physiol
. 2020 Mar;
318(5):L931-L942.
PMID: 32130033
The human airway is protected by an efficient innate defense mechanism that requires healthy secretion of airway surface liquid (ASL) to clear pathogens from the lungs. Most of the ASL...
8.
Capriotti N, Ianowski J, Gioino P, Ons S
J Exp Biol
. 2019 May;
222(Pt 10).
PMID: 31053646
Given that hematophagous insects ingest large quantities of blood in a single meal, they must undergo a rapid post-prandial diuresis in order to maintain homeostasis. In the kissing bug (Hemiptera:...
9.
Luan X, Tam J, Belev G, Jagadeeshan S, Murray B, Hassan N, et al.
Sci Rep
. 2019 Jan;
9(1):540.
PMID: 30679487
Inhaled hypertonic saline (HTS) treatment is used to improve lung health in patients with cystic fibrosis (CF). The current consensus is that the treatment generates an osmotic gradient that draws...
10.
Lam D, Momeni Z, Theaker M, Jagadeeshan S, Yamamoto Y, Ianowski J, et al.
PLoS One
. 2018 Feb;
13(2):e0193312.
PMID: 29474476
Diabetes mellitus is associated with sensory abnormalities, including exacerbated responses to painful (hyperalgesia) or non-painful (allodynia) stimuli. These abnormalities are symptoms of diabetic peripheral neuropathy (DPN), which is the most...