Juan Martin-Caballero
Overview
Explore the profile of Juan Martin-Caballero including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
1197
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Recent Articles
1.
McGrail K, Gonzalez-Sanchez E, Granado-Martinez P, Orsenigo R, Ding Y, Ferrer B, et al.
Mol Oncol
. 2024 Aug;
19(2):329-343.
PMID: 39115053
The mechanisms that work alongside BRAF oncogene in melanoma development, in addition to ultraviolet (UV) radiation (UVR), are of great interest. Analysis of human melanoma tumors [data from The Cancer...
2.
Sinigaglia B, Escudero J, Biagini S, Garcia-Calleja J, Moreno J, Dobon B, et al.
Mol Biol Evol
. 2024 Jan;
41(2).
PMID: 38285634
Rainforest hunter-gatherers from Southeast Asia are characterized by specific morphological features including a particularly dark skin color (D), short stature (S), woolly hair (W), and the presence of steatopygia (S)-fat...
3.
Galindo-Campos M, Lutfi N, Bonnin S, Martinez C, Velasco-Hernandez T, Garcia-Hernandez V, et al.
Blood
. 2021 Aug;
139(2):228-239.
PMID: 34359075
Dysregulation of the c-Myc oncogene occurs in a wide variety of hematologic malignancies, and its overexpression has been linked with aggressive tumor progression. Here, we show that poly (ADP-ribose) polymerase...
4.
Moreno-Lama L, Galindo-Campos M, Martinez C, Comerma L, Vazquez I, Vernet-Tomas M, et al.
Oncogene
. 2020 Feb;
39(13):2835-2843.
PMID: 32001817
Poly(ADP-ribose)-polymerase (PARP)-1 and PARP-2 play an essential role in the DNA damage response. Based on this effect of PARP in the tumor cell itself, PARP inhibitors have emerged as new...
5.
Galindo-Campos M, Bedora-Faure M, Farres J, Lescale C, Moreno-Lama L, Martinez C, et al.
Cell Death Differ
. 2019 Apr;
26(12):2667-2681.
PMID: 30996287
Poly (ADP-ribose) polymerase (PARP)-1 and PARP-2 regulate the function of various DNA-interacting proteins by transferring ADP-ribose emerging from catalytic cleavage of cellular β-NAD. Hence, mice lacking PARP-1 or PARP-2 show...
6.
Salzer M, Lafzi A, Berenguer-Llergo A, Youssif C, Castellanos A, Solanas G, et al.
Cell
. 2018 Nov;
175(6):1575-1590.e22.
PMID: 30415840
During aging, stromal functions are thought to be impaired, but little is known whether this stems from changes of fibroblasts. Using population- and single-cell transcriptomics, as well as long-term lineage...
7.
Buxade M, Huerga Encabo H, Riera-Borrull M, Quintana-Gallardo L, Lopez-Cotarelo P, Tellechea M, et al.
J Exp Med
. 2018 Oct;
215(11):2901-2918.
PMID: 30327417
MHCII in antigen-presenting cells (APCs) is a key regulator of adaptive immune responses. Expression of MHCII genes is controlled by the transcription coactivator CIITA, itself regulated through cell type-specific promoters....
8.
Constitutive Cyclin O deficiency results in penetrant hydrocephalus, impaired growth and infertility
Nunez-Olle M, Jung C, Terre B, Balsiger N, Plata C, Roset R, et al.
Oncotarget
. 2017 Dec;
8(59):99261-99273.
PMID: 29245899
Cyclin O (encoded by ) is a member of the cyclin family with regulatory functions in ciliogenesis and apoptosis. Homozygous mutations have been identified in human patients with Reduced Generation...
9.
Navarro J, Gozalbo-Lopez B, Mendez A, Dantzer F, Schreiber V, Martinez C, et al.
Sci Rep
. 2017 Feb;
7:41962.
PMID: 28181505
The maintenance of T-cell homeostasis must be tightly regulated. Here, we have identified a coordinated role of Poly(ADP-ribose) polymerase-1 (PARP-1) and PARP-2 in maintaining T-lymphocyte number and function. Mice bearing...
10.
Cantarino N, Fernandez-Figueras M, Valero V, Musulen E, Malinverni R, Granada I, et al.
Int J Cancer
. 2016 Apr;
139(5):1106-16.
PMID: 27074337
Squamous cell carcinomas have a range of histopathological manifestations. The parameters that determine this clinically observed heterogeneity are not fully understood. Here, we report the generation of a cell culture...