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Juan M Torres

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Articles 17
Citations 192
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Recent Articles
1.
Otero A, Barrio T, Erana H, Charco J, Betancor M, Diaz-Dominguez C, et al.
PLoS Pathog . 2022 Oct; 18(10):e1010900. PMID: 36206325
The role of the glycosylation status of PrPC in the conversion to its pathological counterpart and on cross-species transmission of prion strains has been widely discussed. Here, we assessed the...
2.
Marin-Moreno A, Fernandez-Borges N, Espinosa J, Andreoletti O, Torres J
Prog Mol Biol Transl Sci . 2017 Aug; 150:181-201. PMID: 28838661
Transmissible spongiform encephalopathies (TSEs) are a group of progressive, invariably fatal diseases that affect the nervous system of many mammals including humans. The key molecular event in the pathogenesis of...
3.
Konold T, Nonno R, Spiropoulos J, Chaplin M, Stack M, Hawkins S, et al.
BMC Res Notes . 2015 Jul; 8:312. PMID: 26205536
Background: The infectious agent responsible for the bovine spongiform encephalopathy (BSE) epidemic in Great Britain is a transmissible spongiform encephalopathy (TSE) strain with uniform properties but the origin of this...
4.
Llorens F, Carulla P, Villa A, Torres J, Fortes P, Ferrer I, et al.
J Neurochem . 2013 May; 127(1):124-38. PMID: 23638794
The prion protein (PrP) plays a key role in prion disease pathogenesis. Although the misfolded and pathologic variant of this protein (PrP(SC)) has been studied in depth, the physiological role...
5.
Juste R, Torres J, Houwers D
Vet Microbiol . 2011 Sep; 154(3-4):422-4. PMID: 21945301
No abstract available.
6.
Larska M, Polak M, Zmudzinski J, Torres J
Brain Res . 2010 Jul; 1351:13-22. PMID: 20654596
Since 2004 cases of atypical bovine spongiform encephalopathy (BSE) in older cattle are recorded on the basis of aberrant glycoprofiles of prion protein resistant to proteolysis (PrP(res)). The nature of...
7.
Morales M, Ramirez M, Cano M, Parraga M, Castilla J, Perez-Ordoyo L, et al.
J Virol . 2008 Dec; 83(5):2397-403. PMID: 19091868
One of the best-studied examples of host-virus coevolution is the release of myxoma virus (MV) for biological control of European rabbits in Australia and Europe. To investigate the genetic basis...
8.
Brun A, Gutierrez-Adan A, Castilla J, Pintado B, Diaz-San Segundo F, Cano M, et al.
J Gen Virol . 2007 May; 88(Pt 6):1842-1849. PMID: 17485546
In this work, transgenic (Tg) mice were generated expressing a bovine prion protein containing five octarepeats (BoPrP(5OR)-Tg). After intracerebral inoculation of bovine spongiform encephalopathy (BSE) inoculum, these mice suffered a...
9.
Martin S, Buron I, Espinosa J, Castilla J, Villalba J, Torres J
Free Radic Biol Med . 2007 Apr; 42(11):1723-9. PMID: 17462540
Oxidative stress and antioxidants play an important role in neurodegenerative diseases. However, the exact participation of antioxidants in the evolution of prion diseases is still largely unknown. The aim of...
10.
Fernandez-Borges N, Brun A, Whitton J, Parra B, Diaz-San Segundo F, Salguero F, et al.
J Virol . 2006 Sep; 80(20):9970-6. PMID: 17005675
Transmissible spongiform encephalopathies (TSEs) can be ameliorated by prion protein (PrP)-specific antibodies, but active immunization is complicated by immune tolerance to the normal cellular host protein (PrP(C)). Here, we show...