Juan Luis Concepcion
Overview
Explore the profile of Juan Luis Concepcion including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
580
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Recent Articles
1.
Rojas-Pirela M, Andrade-Alviarez D, Rojas V, Marcos M, Salete-Granado D, Chacon-Arnaude M, et al.
Open Biol
. 2025 Feb;
15(2):240239.
PMID: 39904372
Glycolysis, present in most organisms, is evolutionarily one of the oldest metabolic pathways. It has great relevance at a physiological level because it is responsible for generating ATP in the...
2.
Rojas-Pirela M, Delgado A, Rondon-Guerrero Y, Caceres A, Michels P, Concepcion J, et al.
Exp Parasitol
. 2023 Jun;
251:108574.
PMID: 37353138
Per-ARNT-Sim (PAS) domains constitute a family of domains present in a wide variety of prokaryotic and eukaryotic organisms. They form part of the structure of various proteins involved in diverse...
3.
Lobo-Rojas A, Quintero-Troconis E, Rondon-Mercado R, Perez-Aguilar M, Concepcion J, Caceres A
Pathogens
. 2022 Oct;
11(10).
PMID: 36297231
In this study, we demonstrate that epimastigotes previously grown in LIT medium supplemented with 20 mM galactose and exposed to sub-lethal concentrations of hydrogen peroxide (100 μM) showed two-fold and...
4.
Valera-Vera E, Concepcion J, Caceres A, Acevedo G, Fernandez M, Hernandez Y, et al.
Mol Immunol
. 2021 Aug;
138:68-75.
PMID: 34364074
Arginine kinase (AK) is an enzyme present in various invertebrates, as well as in some trypanosomatids such as T. cruzi, the etiological agent that causes Chagas disease. In invertebrates, this...
5.
Rojas-Pirela M, Andrade-Alviarez D, Rojas V, Kemmerling U, Caceres A, Michels P, et al.
Open Biol
. 2020 Nov;
10(11):200302.
PMID: 33234025
Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses one...
6.
Gonzalez-Marcano E, Acosta H, Quinones W, Mijares A, Concepcion J
Parasitol Res
. 2020 Oct;
120(4):1421-1428.
PMID: 33098461
Trypanosoma cruzi, the causative agent of Chagas' disease, belongs to the Trypanosomatidae family. The parasite undergoes multiple morphological and metabolic changes during its life cycle, in which it can use...
7.
Madigan R, Majoy S, Ritter K, Concepcion J, Marquez M, Silva S, et al.
J Am Vet Med Assoc
. 2019 Jul;
255(3):317-329.
PMID: 31298647
Objective: To evaluate clinical, serologic, parasitological, and histologic outcomes of dogs with naturally occurring infection treated for 12 months with amiodarone and itraconazole. Animals: 121 dogs from southern Texas and...
8.
Acosta H, Burchmore R, Naula C, Gualdron-Lopez M, Quintero-Troconis E, Caceres A, et al.
Mol Biochem Parasitol
. 2019 Mar;
229:62-74.
PMID: 30831156
In Trypanosoma cruzi, the causal agent of Chagas disease, the first seven steps of glycolysis are compartmentalized in glycosomes, which are authentic but specialized peroxisomes. Besides glycolysis, activity of enzymes...
9.
Rojas-Pirela M, Rigden D, Michels P, Caceres A, Concepcion J, Quinones W
Mol Biochem Parasitol
. 2017 Nov;
219:52-66.
PMID: 29133150
Per-ARNT-Sim (PAS) domains of proteins play important roles as modules for signalling and cellular regulation processes in widely diverse organisms such as Archaea, Bacteria, protists, plants, yeasts, insects and vertebrates....
10.
Garcia-Jordan N, Berrizbeitia M, Rodriguez J, Concepcion J, Caceres A, Quinones W
Cad Saude Publica
. 2017 Nov;
33(10):e00050216.
PMID: 29091170
The current study aimed to determine the seroprevalence of Trypanosoma cruzi infection in Sucre State, Venezuela, and its association with epidemiological risk factors. The cluster sampling design allowed selecting 96...