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Juan Carlos Laguna

Explore the profile of Juan Carlos Laguna including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 712
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Recent Articles
1.
Garcia-Pardo M, Garcia de Herreros M, Laguna J, Gorria T, Lage Y, Gomez A, et al.
Clin Lung Cancer . 2025 Mar; PMID: 40064572
No abstract available.
2.
Irisarri A, Corral A, Perez-Salvador N, Bellver-Sanchis A, Ribalta-Vilella M, Bentanachs R, et al.
Mol Med . 2025 Feb; 31(1):73. PMID: 39984825
This study investigated the effects of fat mass and obesity-associated (FTO) inhibition on cognitive function and metabolic parameters of senescence-accelerated mouse prone 8 (SAMP8) mice fed a high-fat diet (HFD)....
3.
Puertas-Umbert L, Alonso J, Blanco-Casoliva L, Almendra-Pegueros R, Camacho M, Rodriguez-Sinovas A, et al.
Biomed Pharmacother . 2025 Jan; 184:117876. PMID: 39889383
Abdominal aortic aneurysm (AAA) is a prevalent degenerative disease characterized by an exacerbated inflammation and destructive vascular remodeling. Unfortunately, effective pharmacological tools for the treatment of this disease remain a...
4.
Leporati R, Auclin E, Morchon D, Ferriol-Galmes M, Laguna J, Gorria T, et al.
Ther Adv Med Oncol . 2024 Dec; 16:17588359241306940. PMID: 39697619
Background: While targeted therapies have transformed the treatment landscape of oncogene-addicted non-small cell lung cancer (NSCLC), the influence of sex on treatment outcomes remains insufficiently understood. Objectives: This systematic review...
5.
Auclin E, Roulleaux Dugage M, Gorria T, Vauchier C, Thibault C, Laguna J, et al.
Lung Cancer . 2024 Nov; 199:108039. PMID: 39612560
Introduction: LIPI has been strongly correlated with immunotherapy (IT) outcomes in advanced NSCLC. Limited data is available for upfront chemotherapy (CT) + IT combinations. We aimed to study its prognostic...
6.
Segui E, Torres J, Auclin E, Casadevall D, Peiro Carmona S, Aguilar-Company J, et al.
Cancers (Basel) . 2024 Sep; 16(17). PMID: 39272832
Purpose: Inflammation and neutrophils play a central role in both COVID-19 disease and cancer. We aimed to assess the impact of pre-existing tumor-related inflammation on COVID-19 outcomes in patients with...
7.
Di Veroli B, Bentanachs R, Roglans N, Alegret M, Giona L, Profumo E, et al.
Cells . 2024 Aug; 13(15. PMID: 39120278
Sex differences may play a role in the etiopathogenesis and severity of metabolic dysfunction-associated steatotic liver disease (MASLD), a disorder characterized by excessive fat accumulation associated with increased inflammation and...
8.
Laguna J, Tagliamento M, Lambertini M, Hiznay J, Mezquita L
Am Soc Clin Oncol Educ Book . 2024 May; 44(3):e432488. PMID: 38788188
Lung cancer has traditionally been associated with advanced age; however, its increasing incidence among young adults raises concerning questions regarding its etiology and unique considerations for this population. In contrast...
9.
Laguna J, Mezquita L
Med . 2024 Apr; 5(4):281-284. PMID: 38614072
The addition of tiragolumab, an anti-TIGIT inhibitor, to chemotherapy plus atezolizumab demonstrated promising early results for lung cancer. Unfortunately, the phase 3 study SKYSCRAPER-02 did not confirm the anticipated benefit...
10.
Garcia de Herreros M, Laguna J, Padrosa J, Barreto T, Chicote M, Font C, et al.
Diagnostics (Basel) . 2024 Apr; 14(7). PMID: 38611643
Background: Despite the increasing number of ICU admissions among patients with solid tumours, there is a lack of tools with which to identify patients who may benefit from critical support....