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Juan C Zapata

Explore the profile of Juan C Zapata including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 578
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Recent Articles
1.
Gutierrez-Barbosa H, Medina-Moreno S, Perdomo-Celis F, Davis H, Chua J, Zapata J
Pathogens . 2024 Aug; 13(8). PMID: 39204240
Dengue is a significant public health problem with no specific viral treatment. One of the main challenges in studying dengue is the lack of adequate animal models recapitulating human immune...
2.
Gutierrez-Barbosa H, Medina-Moreno S, Perdomo-Celis F, Davis H, Coronel-Ruiz C, Zapata J, et al.
Microorganisms . 2023 Jun; 11(6). PMID: 37375051
Humanized mice are an invaluable tool for investigating human diseases such as cancer, infectious diseases, and graft-versus-host disease (GvHD). However, it is crucial to understand the strengths and limitations of...
3.
Gutierrez-Barbosa H, Medina-Moreno S, Davis H, Bryant J, Chua J, Zapata J
Methods Mol Biol . 2021 Oct; 2409:271-289. PMID: 34709649
Dengue is one of the most prevalent infectious diseases around the world, present in all continents and mainly affecting developing countries. With few tools to fight and study this disease,...
4.
Gutierrez-Barbosa H, Medina-Moreno S, Zapata J, Chua J
Trop Med Infect Dis . 2020 Oct; 5(4). PMID: 33022908
Dengue is a major public health problem in hyperendemic countries like Colombia, the understanding of the epidemiological trends is important for the development of efficient public health policies. We conducted...
5.
Medina-Moreno S, Zapata J, Kashanchi F, Le N, Hassounah S, Mesplede T, et al.
J Glob Antimicrob Resist . 2020 Feb; 20:316-317. PMID: 32061877
No abstract available.
6.
Coronel-Ruiz C, Gutierrez-Barbosa H, Medina-Moreno S, Velandia-Romero M, Chua J, Castellanos J, et al.
Vaccines (Basel) . 2020 Jan; 8(1). PMID: 31979145
Dengue virus (DENV) is an arbovirus of the Flaviviridae family and is an enveloped virion containing a positive sense single-stranded RNA genome. DENV causes dengue fever (DF) which is characterized...
7.
Perdomo-Celis F, Medina-Moreno S, Davis H, Bryant J, Taborda N, Rugeles M, et al.
Immunobiology . 2019 Dec; 225(2):151885. PMID: 31836302
Humanized NOD/SCID/IL-2 receptor γ-chain (huNSG) mice recapitulate some features of human T-cell populations that can be exploited in basic and pre-clinical research. CXCR5 T CD8 T-cells play an important role...
8.
Frohna P, Ratnayake A, Doerr N, Basheer A, Al-Mawsawi L, Kim W, et al.
J Clin Pharmacol . 2019 Aug; 60(2):264-273. PMID: 31465127
Pathologic roles of interleukin (IL)-2, IL-9, and IL-15, have been implicated in multiple T-cell malignancies and autoimmune diseases. BNZ-1 is a selective and simultaneous inhibitor of IL-2, IL-9, and IL-15,...
9.
Affram Y, Zapata J, Gholizadeh Z, Tolbert W, Zhou W, Iglesias-Ussel M, et al.
J Virol . 2019 Aug; 93(21). PMID: 31434734
The negative strand of HIV-1 encodes a highly hydrophobic antisense protein (ASP) with no known homologs. The presence of humoral and cellular immune responses to ASP in HIV-1 patients indicates...
10.
Latinovic O, Neal L, Tagaya Y, Heredia A, Medina-Moreno S, Zapata J, et al.
AIDS Res Hum Retroviruses . 2019 May; 35(8):718-728. PMID: 31099257
Significant progress has been made in the diagnostics and treatment of AIDS since the discovery of the human immunodeficiency virus type 1 (HIV-1) in 1983. The remarkable effectiveness of combined...