Juan Ayllon
Overview
Explore the profile of Juan Ayllon including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
832
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Recent Articles
1.
Aslam S, Rajendran M, Kriti D, Kurland A, Johnson J, van Bakel H, et al.
NPJ Vaccines
. 2023 Feb;
8(1):12.
PMID: 36765053
Influenza B virus (IBV) strains are one of the components of seasonal influenza vaccines in both trivalent and quadrivalent formulations. The vast majority of these vaccines are produced in embryonated...
2.
Erkoreka A, Hernando-Perez J, Ayllon J
Infect Dis Rep
. 2022 Jun;
14(3):453-469.
PMID: 35735759
Using new and original nineteenth-century sources, we analysed the epidemiology, clinical features and virology of the 1889 pandemic, which was referred to at the time as 'Russian flu' or 'Asiatic...
3.
Aydillo T, Escalera A, Strohmeier S, Aslam S, Sanchez-Cespedes J, Ayllon J, et al.
Cell Rep Med
. 2020 Dec;
1(8):100130.
PMID: 33294855
Hemagglutination-inhibitory antibodies are usually highly strain specific with little effect on infection with drifted or shifted strains. The significance of broadly cross-reactive non-HAI anti-influenza antibodies against conserved domains of virus...
4.
Chromikova V, Tan J, Aslam S, Rajabhathor A, Bermudez-Gonzalez M, Ayllon J, et al.
Vaccine
. 2020 Jan;
38(8):1953-1961.
PMID: 31959425
The stalk of the influenza virus hemagglutinin (HA) is an attractive target for antibody-based universal influenza virus vaccine development. While antibodies that target this part of the virus can be...
5.
Munoz-Moreno R, Martinez-Romero C, Blanco-Melo D, Forst C, Nachbagauer R, Benitez A, et al.
Cell Rep
. 2019 Dec;
29(12):3997-4009.e5.
PMID: 31851929
Influenza A viruses (IAVs) have a remarkable tropism in their ability to circulate in both mammalian and avian species. The IAV NS1 protein is a multifunctional virulence factor that inhibits...
6.
Arunkumar G, Ioannou A, Wohlbold T, Meade P, Aslam S, Amanat F, et al.
J Virol
. 2019 Jan;
93(6).
PMID: 30626682
Protection from influenza virus infection is canonically associated with antibodies that neutralize the virus by blocking the interaction between the viral hemagglutinin and host cell receptors. However, protection can also...
7.
Zhao N, Sebastiano V, Moshkina N, Mena N, Hultquist J, Jimenez-Morales D, et al.
Nat Struct Mol Biol
. 2018 Sep;
25(9):885-893.
PMID: 30177761
Viral infection perturbs host cells and can be used to uncover regulatory mechanisms controlling cellular responses and susceptibility to infections. Using cell biological, biochemical, and genetic tools, we reveal that...
8.
White K, Ayllon J, Mena I, Potenski A, Krammer F, Garcia-Sastre A
Vaccine
. 2018 Feb;
36(9):1146-1153.
PMID: 29395518
Vaccination remains the best available prophylaxis to prevent influenza virus infections, yet current inadequacies in influenza virus vaccine manufacturing often lead to vaccine shortages at times when the vaccine is...
9.
Aydillo T, Ayllon J, Pavlisin A, Martinez-Romero C, Tripathi S, Mena I, et al.
J Virol
. 2018 Jan;
92(7).
PMID: 29321309
Recently, two new influenza A-like viruses have been discovered in bats, A/little yellow-shouldered bat/Guatemala/060/2010 (HL17NL10) and A/flat-faced bat/Peru/033/2010 (HL18NL11). The hemagglutinin (HA)-like (HL) and neuraminidase (NA)-like (NL) proteins of these...
10.
Turkington H, Juozapaitis M, Kerry P, Aydillo T, Ayllon J, Garcia-Sastre A, et al.
J Virol
. 2015 Aug;
89(20):10696-701.
PMID: 26246567
We demonstrate that novel bat HL17NL10 and HL18NL11 influenza virus NS1 proteins are effective interferon antagonists but do not block general host gene expression. Solving the RNA-binding domain structures revealed...