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Juan A Lopez

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Articles 61
Citations 1776
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Recent Articles
1.
Arango-Franco C, Ogishi M, Unger S, Delmonte O, Orrego J, Yatim A, et al.
J Clin Invest . 2024 Oct; 134(19). PMID: 39352394
Infants with biallelic IL7R loss-of-function variants have severe combined immune deficiency (SCID) characterized by the absence of autologous T lymphocytes, but normal counts of circulating B and NK cells (T-B+NK+...
2.
Plaza-Florido A, Galvez B, Lopez J, Santos-Lozano A, Zazo S, Rincon-Castanedo C, et al.
Physiol Genomics . 2024 Sep; 56(12):833-844. PMID: 39311839
The impact of exercise on pediatric tumor biology is essentially unknown. We explored the effects of regular exercise on tumor proteome profile (as assessed with liquid chromatography with tandem mass...
3.
Ruiz-Jarabo I, Hernandez-Urcera J, Pereira S, Sobrino I, Lopez J, Planas M
Animals (Basel) . 2024 Aug; 14(16). PMID: 39199862
Achieving sustainable resource use is a priority to meet future challenges. The Gulf of Cádiz, located in the Atlantic waters of southern Europe, is home to a significant fishing fleet...
4.
Martin-Blazquez A, Martin-Lorenzo M, Santiago-Hernandez A, Heredero A, Donado A, Lopez J, et al.
J Proteome Res . 2024 Apr; 23(8):3012-3024. PMID: 38594816
Thoracic aortic aneurysm (TAA) is mainly sporadic and with higher incidence in the presence of a bicuspid aortic valve (BAV) for unknown reasons. The lack of drug therapy to delay...
5.
Rodriguez J, Jorge I, Martinez-Val A, Barrero-Rodriguez R, Magni R, Nunez E, et al.
Comput Struct Biotechnol J . 2024 Jan; 23:452-459. PMID: 38235360
Many bioinformatics tools are available for the quantitative analysis of proteomics experiments. Most of these tools use a dedicated statistical model to derive absolute quantitative protein values from mass spectrometry...
6.
Santamaria R, Cruz-Caballero J, Gkontra P, Jimenez-Montiel A, Clemente C, Lopez J, et al.
Front Cell Dev Biol . 2023 Nov; 11:1256127. PMID: 38020883
Removal of poorly perfused capillaries by pruning contributes to remodeling the microvasculature to optimize oxygen and nutrient delivery. Blood flow drives this process by promoting the intravascular migration of endothelial...
7.
Sanchez-Castillo C, Cuartero M, Fernandez-Rodrigo A, Briz V, Lopez-Garcia S, Jimenez-Sanchez R, et al.
Sci Adv . 2022 Nov; 8(47):eabq8109. PMID: 36417513
Neuronal connectivity and activity-dependent synaptic plasticity are fundamental properties that support brain function and cognitive performance. Phosphatidylinositol 3-kinase (PI3K) intracellular signaling controls multiple mechanisms mediating neuronal growth, synaptic structure, and...
8.
Martinez-Cuadron D, Serrano J, Mariz J, Gil C, Tormo M, Martinez-Sanchez P, et al.
Cancers (Basel) . 2022 Jun; 14(11). PMID: 35681796
This retrospective study investigated outcomes of 404 patients with relapsed/refractory (R/R) FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) acute myeloid leukemia (AML) enrolled in the PETHEMA registry, pre-approval of...
9.
Sun S, Lopez J, Xie Y, Guo W, Liu D, Li L
Comput Struct Biotechnol J . 2022 Apr; 20:1580-1583. PMID: 35422969
The electrostatic features of highly charged biomolecules are crucial and challenging tasks in computational biophysics. The electrostatic calculations by traditional implicit solvent methods are efficient but have difficulties on highly...
10.
Sastre-Oliva T, Corbacho-Alonso N, Albo-Escalona D, Lopez J, Lopez-Almodovar L, Vazquez J, et al.
Antioxidants (Basel) . 2022 Feb; 11(2). PMID: 35204200
Calcific aortic valve and coronary artery diseases are related cardiovascular pathologies in which common processes lead to the calcification of the corresponding affected tissue. Among the mechanisms involved in calcification,...