Ju Rang Woo
Overview
Explore the profile of Ju Rang Woo including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
347
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0
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Recent Articles
1.
Cho Y, Ko I, Kim H, Kim J, Heo K, Na H, et al.
Int J Biol Macromol
. 2025 Jan;
301:140374.
PMID: 39880265
Glucose-regulated protein 94 (GRP94) overexpression plays a critical role in tumor cell survival across various cancers. Previously, we developed K101.1, a fully human antibody targeting cell surface GRP94, which effectively...
2.
Woo J, Bae S, Wales T, Engen J, Lee J, Jang H, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(17):e2401716121.
PMID: 38625937
Serine phosphorylations on insulin receptor substrate 1 (IRS-1) by diverse kinases aoccur widely during obesity-, stress-, and inflammation-induced conditions in models of insulin resistance and type 2 diabetes. In this...
3.
Kim J, Heo K, Kim H, Yoo Y, Cho H, Jang H, et al.
Antiviral Res
. 2023 Mar;
212:105576.
PMID: 36870394
Rapid emergence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has prompted an urgent need for the development of broadly applicable and potently neutralizing antibody platform against...
4.
Ko S, Park S, Sohn M, Jo M, Ko B, Na J, et al.
Exp Mol Med
. 2022 Nov;
54(11):1850-1861.
PMID: 36319752
The pH-selective interaction between the immunoglobulin G (IgG) fragment crystallizable region (Fc region) and the neonatal Fc receptor (FcRn) is critical for prolonging the circulating half-lives of IgG molecules through...
5.
Lee K, Yeo K, Choi S, Lee E, Kim B, Kim S, et al.
IUCrJ
. 2020 Nov;
7(Pt 6):1019-1027.
PMID: 33209316
Protein dimerization or oligomerization resulting from swapping part of the protein between neighboring polypeptide chains is known to play a key role in the regulation of protein function and in...
6.
Son D, Zheng J, Jung Y, Hwang C, Lee H, Woo J, et al.
Theranostics
. 2017 Nov;
7(18):4632-4642.
PMID: 29158850
Signal transducer and activator of transcription-3 (STAT3) plays a pivotal role in cancer biology. Many small-molecule inhibitors that target STAT3 have been developed as potential anticancer drugs. While designing small-molecule...
7.
Woo J, Kim S, Kim K, Jang H, Shoelson S, Park S
Int J Biol Macromol
. 2017 May;
103:965-971.
PMID: 28545963
TBC1D4 (also known as AS160) is a Rab·GTPase-activating protein (RabGAP) which functions in insulin signaling. TBC1D4 is critical for translocation of glucose transporter 4 (GLUT4), from an inactive, intracellular, vesicle-bound...
8.
Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway
Zheng J, Son D, Gu S, Woo J, Ham Y, Lee H, et al.
Sci Rep
. 2016 May;
6:26357.
PMID: 27198178
Piperlongumine has anti-cancer activity in numerous cancer cell lines via various signaling pathways. But there has been no study regarding the mechanisms of PL on the lung cancer yet. Thus,...
9.
Park J, Lim M, Woo J, Kim J, Lee G
Biotechnol Prog
. 2016 Apr;
32(5):1113-1122.
PMID: 27114230
To investigate the effect of dextran sulfate (DS), a widely used anti-aggregation agent, on cell growth and monoclonal antibody (mAb) production including the quality attributes, DS with the three different...
10.
Lee B, Kim M, Pae M, Yamamoto Y, Eberle D, Shimada T, et al.
Cell Metab
. 2016 Apr;
23(4):685-98.
PMID: 27050305
Obesity-induced inflammation mediated by immune cells in adipose tissue appears to participate in the pathogenesis of insulin resistance. We show that natural killer (NK) cells in adipose tissue play an...