Jouke Jan Hottenga
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Explore the profile of Jouke Jan Hottenga including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Hubers N, Drouard G, Jansen R, Pool R, Hottenga J, Ollikainen M, et al.
Am J Med Genet A
. 2024 Dec;
197(4):e63971.
PMID: 39676692
Monozygotic (MZ) and dizygotic (DZ) twins are studied to understand genetic and environmental influences on complex traits, however the mechanisms behind twinning are not completely understood. (Epi)genomic studies identified SNPs...
2.
Willems Y, Raffington L, Ligthart L, Pool R, Hottenga J, Finkenauer C, et al.
Front Psychiatry
. 2024 May;
15:1388264.
PMID: 38693999
Background: Difficulty with self-control, or the ability to alter impulses and behavior in a goal-directed way, predicts interpersonal conflict, lower socioeconomic attainments, and more adverse health outcomes. Etiological understanding, and...
3.
Karjalainen M, Karthikeyan S, Oliver-Williams C, Sliz E, Allara E, Fung W, et al.
Nature
. 2024 Mar;
628(8006):130-138.
PMID: 38448586
Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism. This detailed knowledge of the genetic determinants of systemic metabolism has been...
4.
Drouard G, Hagenbeek F, Whipp A, Pool R, Hottenga J, Jansen R, et al.
BMC Med
. 2023 Dec;
21(1):508.
PMID: 38129841
Background: The influence of genetics and environment on the association of the plasma proteome with body mass index (BMI) and changes in BMI remains underexplored, and the links to other...
5.
Van Asselt A, Beck J, Finnicum C, Johnson B, Kallsen N, Hottenga J, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834090
The field of DNA methylation research is rapidly evolving, focusing on disease and phenotype changes over time using methylation measurements from diverse tissue sources and multiple array platforms. Consequently, identifying...
6.
Hubers N, Hagenbeek F, Pool R, Dejean S, Harms A, Roetman P, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2023 Aug;
195(2):e32955.
PMID: 37534875
The evolving field of multi-omics combines data and provides methods for simultaneous analysis across several omics levels. Here, we integrated genomics (transmitted and non-transmitted polygenic scores [PGSs]), epigenomics, and metabolomics...
7.
Beck J, Ahmed T, Finnicum C, Zwinderman K, Ehli E, Boomsma D, et al.
Genes (Basel)
. 2023 Jul;
14(7).
PMID: 37510400
Accurate inference of genetic ancestry is crucial for population-based association studies, accounting for population heterogeneity and structure. This study analyzes genome-wide SNP data from the Netherlands Twin Register to compare...
8.
Drouard G, Hagenbeek F, Whipp A, Pool R, Hottenga J, Jansen R, et al.
medRxiv
. 2023 Jul;
PMID: 37425750
Background: The influence of genetics and environment on the association of the plasma proteome with body mass index (BMI) and changes in BMI remain underexplored, and the links to other...
9.
Graham S, Clarke S, Wu K, Kanoni S, Zajac G, Ramdas S, et al.
Nature
. 2023 May;
618(7965):E19-E20.
PMID: 37237109
No abstract available.
10.
Mathieson I, Day F, Barban N, Tropf F, Brazel D, Vaez A, et al.
Nat Hum Behav
. 2023 Mar;
7(5):790-801.
PMID: 36864135
Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, we identified 43 genomic loci...