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Josip S Herman

Explore the profile of Josip S Herman including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 924
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Recent Articles
1.
Hochrein S, Wu H, Eckstein M, Arrigoni L, Herman J, Schumacher F, et al.
Cell Metab . 2022 Mar; 34(4):516-532.e11. PMID: 35316657
Metabolic reprogramming is a hallmark of activated T cells. The switch from oxidative phosphorylation to aerobic glycolysis provides energy and intermediary metabolites for the biosynthesis of macromolecules to support clonal...
2.
Clapes T, Polyzou A, Prater P, Sagar , Morales-Hernandez A, Galvao Ferrarini M, et al.
Nat Cell Biol . 2021 Oct; 23(12):1338. PMID: 34611323
No abstract available.
3.
Clapes T, Polyzou A, Prater P, Sagar , Morales-Hernandez A, Galvao Ferrarini M, et al.
Nat Cell Biol . 2021 Jul; 23(7):704-717. PMID: 34253898
Haematopoietic stem cells (HSCs) are normally quiescent, but have evolved mechanisms to respond to stress. Here, we evaluate haematopoietic regeneration induced by chemotherapy. We detect robust chromatin reorganization followed by...
4.
Ramamoorthy S, Kometani K, Herman J, Bayer M, Boller S, Edwards-Hicks J, et al.
Genes Dev . 2020 Oct; 34(21-22):1503-1519. PMID: 33004416
and mutations are associated with the development of B progenitor acute lymphoblastic leukemia (B-ALL) in humans. To understand the molecular networks driving leukemia in the (dHet) mouse model for B-ALL,...
5.
Zeis P, Lian M, Fan X, Herman J, Hernandez D, Gentek R, et al.
Immunity . 2020 Oct; 53(4):775-792.e9. PMID: 33002412
Innate lymphoid cells (ILCs) are generated early during ontogeny and persist predominantly as tissue-resident cells. Here, we examined how ILCs are maintained and renewed within tissues. We generated a single...
6.
Sagar , Pokrovskii M, Herman J, Naik S, Sock E, Zeis P, et al.
EMBO J . 2020 Jul; 39(13):e104159. PMID: 32627520
γδ T cells with distinct properties develop in the embryonic and adult thymus and have been identified as critical players in a broad range of infections, antitumor surveillance, autoimmune diseases,...
7.
Aizarani N, Saviano A, Sagar , Mailly L, Durand S, Herman J, et al.
Nature . 2019 Jul; 572(7768):199-204. PMID: 31292543
The human liver is an essential multifunctional organ. The incidence of liver diseases is rising and there are limited treatment options. However, the cellular composition of the liver remains poorly...
8.
Herman J, Sagar , Grun D
Nat Methods . 2018 Apr; 15(5):379-386. PMID: 29630061
To understand stem cell differentiation along multiple lineages, it is necessary to resolve heterogeneous cellular states and the ancestral relationships between them. We developed a robotic miniaturized CEL-Seq2 implementation to...
9.
Harbauer A, Opalinska M, Gerbeth C, Herman J, Rao S, Schonfisch B, et al.
Science . 2014 Nov; 346(6213):1109-13. PMID: 25378463
Mitochondria play central roles in cellular energy conversion, metabolism, and apoptosis. Mitochondria import more than 1000 different proteins from the cytosol. It is unknown if the mitochondrial protein import machinery...