Joshua Wheeler
Overview
Explore the profile of Joshua Wheeler including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
348
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0
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Recent Articles
1.
Chandler H, Wheeler J, Escott-Price V, Murphy K, Lancaster T
Alzheimers Dement
. 2024 Dec;
21(2):e14455.
PMID: 39737667
Introduction: White matter hyperintensity volumes (WMHVs) are disproportionally prevalent in individuals with Alzheimer's disease (AD), potentially reflecting neurovascular injury. We quantify the association between AD polygenic risk score (AD-PRS) and...
2.
Rogawski D, Wheeler J, Nie E, Zhu W, Villanueva E, Coffey G, et al.
Acta Neuropathol Commun
. 2024 Jan;
12(1):15.
PMID: 38254244
Brain metastases occur in 1% of sarcoma cases and are associated with a median overall survival of 6 months. We report a rare case of a brain metastasis with unique...
3.
van der Wal D, Jhun I, Laklouk I, Nirschl J, Richer L, Rojansky R, et al.
NPJ Digit Med
. 2021 Oct;
4(1):145.
PMID: 34620993
Biology has become a prime area for the deployment of deep learning and artificial intelligence (AI), enabled largely by the massive data sets that the field can generate. Key to...
4.
Lester E, Ooi F, Bakkar N, Ayers J, Woerman A, Wheeler J, et al.
Neuron
. 2021 Apr;
109(10):1675-1691.e9.
PMID: 33848474
Tau aggregates contribute to neurodegenerative diseases, including frontotemporal dementia and Alzheimer's disease (AD). Although RNA promotes tau aggregation in vitro, whether tau aggregates in cells contain RNA is unknown. We...
5.
Minnema L, Wheeler J, Enomoto M, Pitake S, Mishra S, Lascelles B
Front Neurosci
. 2020 Mar;
14:77.
PMID: 32116521
Arthritis, including osteoarthritis (OA) and other musculoskeletal-associated pain, is a worldwide problem, however, effective drug options are limited. Several receptors, neurotransmitters, and endogenous mediators have been identified in rodent models,...
6.
Johnson B, Avval T, Wheeler J, Anderson H, Diwan A, Stowers K, et al.
Langmuir
. 2020 Feb;
36(8):1878-1886.
PMID: 32013448
Here, we address the issue of finding correct CF/CF area ratios from X-ray photoelectron spectroscopy (XPS) C 1s narrow scans of materials containing -CHCH(CF)CF ( = 0, 1, 2, ...)...
7.
Hauser M, Aboobakar I, Liu Y, Miura S, Whigham B, Challa P, et al.
Hum Mol Genet
. 2015 Aug;
24(22):6552-63.
PMID: 26307087
Exfoliation syndrome (XFS) is a common, age-related, systemic fibrillinopathy. It greatly increases risk of exfoliation glaucoma (XFG), a major worldwide cause of irreversible blindness. Coding variants in the lysyl oxidase-like...
8.
Liu Y, Allingham R, Qin X, Layfield D, Dellinger A, Gibson J, et al.
Invest Ophthalmol Vis Sci
. 2013 Sep;
54(9):6382-9.
PMID: 24003086
Purpose: To identify the specific genes in human trabecular meshwork (TM) related to POAG. Methods: Primary open-angle glaucoma TM specimens were obtained from routine trabeculectomy surgery. Nonglaucomatous control TM specimens...
9.
Liu Y, Hauser M, Akafo S, Qin X, Miura S, Gibson J, et al.
Invest Ophthalmol Vis Sci
. 2013 Aug;
54(9):6248-54.
PMID: 23963167
Purpose: Multiple genes have been associated with primary open angle glaucoma (POAG) in Caucasian populations. We now examine the association of these loci in populations of African ancestry, populations at...
10.
Wheeler J, Hauser M, Afshari N, Allingham R, Liu Y
Reprod Syst Sex Disord
. 2013 Jun;
(Suppl 6).
PMID: 23795306
Keratoconus is the most common ectatic disorder of the corneal. Genetic and environmental factors may contribute to its pathogenesis. The focus of this article is to summarize current research into...