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Joshua T Eggold

Explore the profile of Joshua T Eggold including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 265
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Recent Articles
1.
Eggold J, Chow S, Melemenidis S, Wang J, Natarajan S, Loo P, et al.
Mol Cancer Ther . 2021 Dec; 21(2):371-381. PMID: 34866044
Treatment of advanced ovarian cancer using PD-1/PD-L1 immune checkpoint blockade shows promise; however, current clinical trials are limited by modest response rates. Radiotherapy has been shown to synergize with PD-1/PD-L1...
2.
Qian J, LeSavage B, Hubka K, Ma C, Natarajan S, Eggold J, et al.
J Clin Invest . 2021 Aug; 131(16). PMID: 34396988
Ovarian cancer is the leading cause of gynecological malignancy-related deaths, due to its widespread intraperitoneal metastases and acquired chemoresistance. Mesothelial cells are an important cellular component of the ovarian cancer...
3.
Levy K, Natarajan S, Wang J, Chow S, Eggold J, Loo P, et al.
Sci Rep . 2020 Dec; 10(1):21600. PMID: 33303827
Radiation therapy is the most effective cytotoxic therapy for localized tumors. However, normal tissue toxicity limits the radiation dose and the curative potential of radiation therapy when treating larger target...
4.
Natarajan S, Foreman K, Soriano M, Rossen N, Shehade H, Fregoso D, et al.
Cancer Res . 2019 Mar; 79(9):2271-2284. PMID: 30862717
Peritoneal metastases are the leading cause of morbidity and mortality in high-grade serous ovarian cancer (HGSOC). Accumulating evidence suggests that mesothelial cells are an important component of the metastatic microenvironment...
5.
Eggold J, Rankin E
Bone . 2018 Mar; 119:36-41. PMID: 29551752
The regulation of erythropoiesis in the bone marrow microenvironment is a carefully orchestrated process that is dependent upon both systemic and local cues. Systemic erythropoietin (EPO) production by renal interstitial...
6.
Chen C, Shin J, Eggold J, Chung M, Zhang L, Lee J, et al.
Oncotarget . 2016 Sep; 7(43):70738-70749. PMID: 27683113
Oral squamous cell carcinoma (OSCC) is a highly invasive and metastatic malignancy. The nerve growth factor receptor (NGFR) has been observed to be expressed on a subset of cells in...