Joshua R Huot
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Explore the profile of Joshua R Huot including associated specialties, affiliations and a list of published articles.
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32
Citations
329
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Recent Articles
1.
GL261 glioblastoma induces delayed body weight gain and stunted skeletal muscle growth in young mice
Huot J, Jamnick N, Pin F, Livingston P, Callaway C, Bonetto A
bioRxiv
. 2025 Feb;
PMID: 39990490
Introduction: The survival rate for children and adolescents has increased to over 85%. However, there is limited understanding of the impact of pediatric cancers on muscle development and physiology. Given...
2.
Thibaut M, Roumain M, Piron E, Gillard J, Loriot A, Neyrinck A, et al.
Gut Microbes
. 2025 Jan;
17(1):2449586.
PMID: 39780051
Alterations in bile acid profile and pathways contribute to hepatic inflammation in cancer cachexia, a syndrome worsening the prognosis of cancer patients. As the gut microbiota impinges on host metabolism...
3.
Jheng J, DesJardin J, Chen Y, Huot J, Bai Y, Cook T, et al.
Arterioscler Thromb Vasc Biol
. 2024 May;
44(7):1570-1583.
PMID: 38813697
Background: Pulmonary hypertension (PH) represents an important phenotype in heart failure with preserved ejection fraction (HFpEF). However, management of PH-HFpEF is challenging because mechanisms involved in the regulation of PH-HFpEF...
4.
Jheng J, Bai Y, Noda K, Huot J, Cook T, Fisher A, et al.
Circulation
. 2024 May;
150(11):867-883.
PMID: 38804138
Background: Pulmonary hypertension (PH) is a major complication linked to adverse outcomes in heart failure with preserved ejection fraction (HFpEF), yet no specific therapies exist for PH associated with HFpEF...
5.
Huot J, Livingston P, Pin F, Thomas C, Jamnick N, Callaway C, et al.
Function (Oxf)
. 2024 May;
5(3):zqae011.
PMID: 38706958
Thanks to recent progress in cancer research, most children treated for cancer survive into adulthood. Nevertheless, the long-term consequences of anticancer agents are understudied, especially in the pediatric population. We...
6.
Galiana-Melendez F, Huot J
Curr Osteoporos Rep
. 2024 Apr;
22(3):318-329.
PMID: 38649653
Purpose Of Review: The purpose of this review is to discuss the musculoskeletal consequences of cancer, including those that occur in the absence of bone metastases. Recent Findings: Cancer patients...
7.
Shimonty A, Pin F, Prideaux M, Peng G, Huot J, Kim H, et al.
bioRxiv
. 2023 Nov;
PMID: 37986762
Irisin, released from exercised muscle, has been shown to have beneficial effects on numerous tissues but its effects on bone are unclear. We found significant sex and genotype differences in...
8.
Shimonty A, Bonewald L, Huot J
Calcif Tissue Int
. 2023 May;
113(1):21-38.
PMID: 37193929
Maintenance of skeletal health is tightly regulated by osteocytes, osteoblasts, and osteoclasts via coordinated secretion of bone-derived factors, termed osteokines. Disruption of this coordinated process due to aging and metabolic...
9.
Dolly A, Potgens S, Thibaut M, Neyrinck A, de Castro G, Galbert C, et al.
J Cachexia Sarcopenia Muscle
. 2023 May;
14(3):1569-1582.
PMID: 37127348
Background: The aryl hydrocarbon receptor (AHR) is expressed in the intestine and liver, where it has pleiotropic functions and target genes. This study aims to explore the potential implication of...
10.
Huot J, Baumfalk D, Resendiz A, Bonetto A, Smuder A, Penna F
Antioxid Redox Signal
. 2022 Oct;
38(4-6):352-370.
PMID: 36310444
Cancer is frequently associated with the early appearance of cachexia, a multifactorial wasting syndrome. If not present at diagnosis, cachexia develops either as a result of tumor progression or as...