Joshua M Thiede
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Explore the profile of Joshua M Thiede including associated specialties, affiliations and a list of published articles.
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16
Citations
352
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Recent Articles
1.
Thiede J, Dick J, Jarjour N, Krishna V, Qian L, Sangala J, et al.
Immunohorizons
. 2024 Sep;
8(9):712-720.
PMID: 39287601
Many mouse models of SARS-CoV-2 infection involve expression of the human ACE2 protein, the entry receptor for SARS-CoV-2 Spike protein, in mouse tissues. However, most of these models suffer from...
2.
Gress A, Ronayne C, Thiede J, Meyerholz D, Okurut S, Stumpf J, et al.
Nat Commun
. 2023 Dec;
14(1):8423.
PMID: 38110410
After Mycobacterium tuberculosis (Mtb) infection, many effector T cells traffic to the lungs, but few become activated. Here we use an antigen receptor reporter mouse (Nur77-GFP) to identify recently activated...
3.
Cole M, Howe M, Buonomo J, Sharma S, Lamont E, Brody S, et al.
Chemistry
. 2022 Jun;
28(51):e202200995.
PMID: 35697660
Tuberculosis (TB) is a leading source of infectious disease mortality globally. Antibiotic-resistant strains comprise an estimated 10 % of new TB cases and present an urgent need for novel therapeutics....
4.
Thiede J, Dillon N, Howe M, Aflakpui R, Modlin S, Hoffner S, et al.
mBio
. 2022 Feb;
13(1):e0043921.
PMID: 35100871
Pyrazinamide (PZA) plays a crucial role in first-line tuberculosis drug therapy. Unlike other antimicrobial agents, PZA is active against Mycobacterium tuberculosis only at low pH. The basis for this conditional...
5.
Ubah O, Lake E, Gunaratne G, Gallant J, Fernie M, Robertson A, et al.
Nat Commun
. 2021 Dec;
12(1):7325.
PMID: 34916516
Single-domain Variable New Antigen Receptors (VNARs) from the immune system of sharks are the smallest naturally occurring binding domains found in nature. Possessing flexible paratopes that can recognize protein motifs...
6.
Matchett W, Joag V, Stolley J, Shepherd F, Quarnstrom C, Mickelson C, et al.
J Immunol
. 2021 Jul;
207(2):376-379.
PMID: 34193597
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing Abs target the receptor binding domain of the spike (S) protein, a focus of successful vaccine...
7.
Matchett W, Joag V, Stolley J, Shepherd F, Quarnstrom C, Mickelson C, et al.
bioRxiv
. 2021 May;
PMID: 33948591
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing antibodies target the receptor binding domain of the spike (S) protein, a focus of successful vaccine...
8.
Fiege J, Thiede J, Nanda H, Matchett W, Moore P, Montanari N, et al.
PLoS Pathog
. 2021 Jan;
17(1):e1009292.
PMID: 33507952
The human airway epithelium is the initial site of SARS-CoV-2 infection. We used flow cytometry and single cell RNA-sequencing to understand how the heterogeneity of this diverse cell population contributes...
9.
Thiede J, Gress A, Libby S, Ronayne C, Matchett W, Noren B, et al.
J Infect Dis
. 2021 Jan;
223(8):1339-1344.
PMID: 33476387
Coronavirus disease 2019 (COVID-19) outcomes are linked to host immune responses and may be affected by antiviral therapy. We investigated antibody and cytokine responses in ACTT-1 study participants enrolled at...
10.
Fiege J, Thiede J, Nanda H, Matchett W, Moore P, Montanari N, et al.
bioRxiv
. 2020 Oct;
PMID: 33106802
The human airway epithelium is the initial site of SARS-CoV-2 infection. We used flow cytometry and single cell RNA-sequencing to understand how the heterogeneity of this diverse cell population contributes...