Joshua M Sopp
Overview
Explore the profile of Joshua M Sopp including associated specialties, affiliations and a list of published articles.
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3
Citations
44
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Recent Articles
1.
Sopp J, Peters S, Rowley T, Oldham R, James S, Mockridge I, et al.
Commun Biol
. 2021 Sep;
4(1):1031.
PMID: 34475514
The majority of depleting monoclonal antibody (mAb) drugs elicit responses via Fc-FcγR and Fc-C1q interactions. Optimal C1q interaction is achieved through hexameric Fc:Fc interactions at the target cell surface. Herein...
2.
Hussain K, Hargreaves C, Rowley T, Sopp J, Latham K, Bhatta P, et al.
Front Immunol
. 2019 Mar;
10:390.
PMID: 30899264
Monoclonal antibody (mAb) immunotherapy has transformed the treatment of allergy, autoimmunity, and cancer. The interaction of mAb with Fc gamma receptors (FcγR) is often critical for efficacy. The genes encoding...
3.
Rowley T, Peters S, Aylott M, Griffin R, Davies N, Healy L, et al.
Commun Biol
. 2018 Oct;
1:146.
PMID: 30272022
Autoantibody-mediated diseases are currently treated with intravenous immunoglobulin, which is thought to act in part via blockade of Fc gamma receptors, thereby inhibiting autoantibody effector functions and subsequent pathology. We...