Joshua M Schmidt
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Explore the profile of Joshua M Schmidt including associated specialties, affiliations and a list of published articles.
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22
Citations
500
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Recent Articles
1.
Ostridge H, Fontsere C, Lizano E, Soto D, Schmidt J, Saxena V, et al.
bioRxiv
. 2024 Jul;
PMID: 39026872
How populations adapt to their environment is a fundamental question in biology. Yet we know surprisingly little about this process, especially for endangered species such as non-human great apes. Chimpanzees,...
2.
Johnson O, Tobler R, Schmidt J, Huber C
Mol Ecol Resour
. 2024 Jan;
24(3):e13930.
PMID: 38247258
Population genetic simulation has emerged as a common tool for investigating increasingly complex evolutionary and demographic models. Software capable of handling high-level model complexity has recently been developed, and the...
3.
Hollitt G, Qassim A, Thomson D, Schmidt J, Nguyen T, Landers J, et al.
BMC Ophthalmol
. 2023 Oct;
23(1):431.
PMID: 37875865
Background: Glaucoma and age-related macular degeneration (AMD) account for a substantial portion of global blindness. Both conditions are highly heritable, with recognised monogenic and polygenic inheritance patterns. Current screening guidelines...
4.
Mullany S, Diaz-Torres S, Schmidt J, Thomson D, Qassim A, Marshall H, et al.
Ophthalmol Sci
. 2023 Apr;
3(3):100287.
PMID: 37007646
Purpose: To elucidate a potential association between the apolipoprotein E () E4 allele and glaucoma prevalence in large cohorts. Design: A cross-sectional analysis of baseline and prospectively collected cohort data....
5.
Johnson O, Tobler R, Schmidt J, Huber C
Trends Genet
. 2023 Mar;
39(6):491-504.
PMID: 36890036
Recent studies of cosmopolitan Drosophila populations have found hundreds to thousands of genetic loci with seasonally fluctuating allele frequencies, bringing temporally fluctuating selection to the forefront of the historical debate...
6.
Aboobakar I, Kinzy T, Zhao Y, Fan B, Pasquale L, Qassim A, et al.
Ophthalmology
. 2023 Feb;
130(7):756-763.
PMID: 36813040
Purpose: Genetic variants in regions that include the mitochondrial genes thioredoxin reductase 2 (TXNRD2) and malic enzyme 3 (ME3) are associated with primary open-angle glaucoma (POAG) in genome-wide association studies...
7.
Mullany S, Marshall H, Diaz-Torres S, Berry E, Schmidt J, Thomson D, et al.
Ophthalmol Sci
. 2022 Oct;
2(2):100159.
PMID: 36249683
Purpose: To investigate the association between the apolipoprotein E () E4 dementia-risk allele and prospective longitudinal retinal thinning in a cohort study of suspect and early manifest glaucoma. Design: Retrospective...
8.
Pawar H, Ostridge H, Schmidt J, Andres A
PLoS Genet
. 2022 Aug;
18(8):e1010337.
PMID: 36007015
Central and eastern chimpanzees are infected with Simian Immunodeficiency Virus (SIV) in the wild, typically without developing acute immunodeficiency. Yet the recent zoonotic transmission of chimpanzee SIV to humans, which...
9.
Souzeau E, Siggs O, Mullany S, Schmidt J, Hassall M, Dubowsky A, et al.
Mol Genet Genomic Med
. 2022 Aug;
10(10):e2023.
PMID: 35985662
Corneal dystrophies describe a clinically and genetically heterogeneous group of inherited disorders. The International Classification of Corneal Dystrophies (IC3D) lists 22 types of corneal dystrophy, 17 of which have been...
10.
Fontsere C, Kuhlwilm M, Morcillo-Suarez C, Alvarez-Estape M, Lester J, Gratton P, et al.
Cell Genom
. 2022 Jun;
2(6):None.
PMID: 35711737
Knowledge on the population history of endangered species is critical for conservation, but whole-genome data on chimpanzees () is geographically sparse. Here, we produced the first non-invasive geolocalized catalog of...