Joshua M Lorenz-Guertin
Overview
Explore the profile of Joshua M Lorenz-Guertin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
112
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lorenz-Guertin J, Povysheva N, Chapman C, MacDonald M, Fazzari M, Nigam A, et al.
Neurobiol Dis
. 2023 Aug;
185:106248.
PMID: 37536384
Benzodiazepine (BZ) drugs treat seizures, anxiety, insomnia, and alcohol withdrawal by potentiating γ2 subunit containing GABA type A receptors (GABARs). BZ clinical use is hampered by tolerance and withdrawal symptoms...
2.
Lorenz-Guertin J, Bambino M, Das S, Weintraub S, Jacob T
Front Cell Neurosci
. 2019 May;
13:163.
PMID: 31080408
Despite 50+ years of clinical use as anxiolytics, anti-convulsants, and sedative/hypnotic agents, the mechanisms underlying benzodiazepine (BZD) tolerance are poorly understood. BZDs potentiate the actions of gamma-aminobutyric acid (GABA), the...
3.
Lorenz-Guertin J, Bambino M, Jacob T
Front Cell Neurosci
. 2018 Sep;
12:265.
PMID: 30190672
GABA type A receptors (GABARs) mediate the majority of fast inhibitory neurotransmission in the central nervous system (CNS). Most prevalent as heteropentamers composed of two α, two β, and a...
4.
Brady M, Pilli J, Lorenz-Guertin J, Das S, Moon C, Graff N, et al.
Neuropharmacology
. 2017 Oct;
128:324-339.
PMID: 29074304
γ-aminobutyric acid (GABA) begins as the key excitatory neurotransmitter in newly forming circuits, with chloride efflux from GABA type A receptors (GABARs) producing membrane depolarization, which promotes calcium entry, dendritic...
5.
Lorenz-Guertin J, Wilcox M, Zhang M, Larsen M, Pilli J, Schmidt B, et al.
J Cell Sci
. 2017 Oct;
130(22):3933-3945.
PMID: 29025969
Live-cell imaging methods can provide critical real-time receptor trafficking measurements. Here, we describe an optical tool to study synaptic γ-aminobutyric acid (GABA) type A receptor (GABAR) dynamics through adaptable fluorescent-tracking...
6.
Lorenz-Guertin J, Jacob T
Dev Neurobiol
. 2017 Sep;
78(3):238-270.
PMID: 28901728
Ubiquitous expression of GABA type A receptors (GABA R) in the central nervous system establishes their central role in coordinating most aspects of neural function and development. Dysregulation of GABAergic...
7.
Leung W, Shaffer C, Chen E, Quisenberry T, Ko K, Braverman J, et al.
G3 (Bethesda)
. 2017 Jul;
7(8):2439-2460.
PMID: 28667019
The discordance between genome size and the complexity of eukaryotes can partly be attributed to differences in repeat density. The Muller F element (∼5.2 Mb) is the smallest chromosome in...