Joshua D Campbell
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Explore the profile of Joshua D Campbell including associated specialties, affiliations and a list of published articles.
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65
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2736
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Recent Articles
11.
ONeill N, Stein T, Hu J, Rehman H, Campbell J, Yajima M, et al.
BMC Bioinformatics
. 2023 Sep;
24(1):349.
PMID: 37726653
Background: Quantifying cell-type abundance in bulk tissue RNA-sequencing enables researchers to better understand complex systems. Newer deconvolution methodologies, such as MuSiC, use cell-type signatures derived from single-cell RNA-sequencing (scRNA-seq) data...
12.
Wang Y, Sarfraz I, Pervaiz N, Hong R, Koga Y, Akavoor V, et al.
Patterns (N Y)
. 2023 Aug;
4(8):100814.
PMID: 37602214
Analysis of single-cell RNA sequencing (scRNA-seq) data can reveal novel insights into the heterogeneity of complex biological systems. Many tools and workflows have been developed to perform different types of...
13.
Pavel A, Garrison C, Luo L, Liu G, Taub D, Xiao J, et al.
Sci Rep
. 2023 Aug;
13(1):13076.
PMID: 37567908
Chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) are clinically and molecularly heterogeneous diseases. We utilized clustering and integrative network analyses to elucidate roles for microRNAs (miRNAs) and...
14.
Arceneaux D, Chen Z, Simmons A, Heiser C, Southard-Smith A, Brenan M, et al.
iScience
. 2023 Jul;
26(7):107242.
PMID: 37496679
Droplet-based single-cell RNA-seq (scRNA-seq) data are plagued by ambient contaminations caused by nucleic acid material released by dead and dying cells. This material is mixed into the buffer and is...
15.
Yanagawa J, Tran L, Salehi-Rad R, Lim R, Dumitras C, Fung E, et al.
Cancer Res
. 2023 Jul;
83(19):3305-3319.
PMID: 37477508
Significance: Analysis of a spectrum of subsolid pulmonary nodules by single-cell RNA sequencing provides insights into the immune regulation and cell-cell interactions in the tumor microenvironment during early lung tumor...
16.
Wang Y, Sarfraz I, Teh W, Sokolov A, Herb B, Creasy H, et al.
bioRxiv
. 2023 Mar;
PMID: 36945543
A large number of genomic and imaging datasets are being produced by consortia that seek to characterize healthy and disease tissues at single-cell resolution. While much effort has been devoted...
17.
Yin Y, Yajima M, Campbell J
bioRxiv
. 2023 Mar;
PMID: 36865227
Assays such as CITE-seq can measure the abundance of cell surface proteins on individual cells using antibody derived tags (ADTs). However, many ADTs have high levels of background noise that...
18.
Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, et al.
Sci Rep
. 2022 Oct;
12(1):18168.
PMID: 36307504
SARS-CoV-2 infection and disease severity are influenced by viral entry (VE) gene expression patterns in the airway epithelium. The similarities and differences of VE gene expression (ACE2, TMPRSS2, and CTSL)...
19.
Wang Z, Yang S, Koga Y, Corbett S, Shea C, Johnson W, et al.
NAR Genom Bioinform
. 2022 Sep;
4(3):lqac066.
PMID: 36110899
Single-cell RNA-seq (scRNA-seq) has emerged as a powerful technique to quantify gene expression in individual cells and to elucidate the molecular and cellular building blocks of complex tissues. We developed...
20.
Vittoria M, Kingston N, Kotynkova K, Xia E, Hong R, Huang L, et al.
Nat Commun
. 2022 Jun;
13(1):3732.
PMID: 35768444
Melanoma is commonly driven by activating mutations in the MAP kinase BRAF; however, oncogenic BRAF alone is insufficient to promote melanomagenesis. Instead, its expression induces a transient proliferative burst that...