Joshua C Grieger
Overview
Explore the profile of Joshua C Grieger including associated specialties, affiliations and a list of published articles.
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17
Citations
1539
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Recent Articles
11.
Li W, Zhang L, Johnson J, Zhijian W, Grieger J, Ping-Jie X, et al.
Mol Ther
. 2009 Jul;
17(12):2067-77.
PMID: 19603002
Recombinant adeno-associated virus (AAV) vectors expressing the cystic fibrosis transmembrane conductance regulator (CFTR) gene have been used to deliver CFTR to the airway epithelium of cystic fibrosis (CF) patients. However,...
12.
Grieger J, Johnson J, Gurda-Whitaker B, Agbandje-Mckenna M, Samulski R
J Virol
. 2007 May;
81(15):7833-43.
PMID: 17507473
Over the past 2 decades, significant effort has been dedicated to the development of adeno-associated virus (AAV) as a vector for human gene therapy. However, understanding of the virus with...
13.
Grieger J, Choi V, Samulski R
Nat Protoc
. 2007 Apr;
1(3):1412-28.
PMID: 17406430
The adeno-associated virus (AAV) is one of the most promising viral vectors for human gene therapy. As with any potential therapeutic system, a thorough understanding of it at the in...
14.
Wu Z, Asokan A, Grieger J, Govindasamy L, Agbandje-Mckenna M, Samulski R
J Virol
. 2006 Sep;
80(22):11393-7.
PMID: 16943302
Despite the high degree of sequence homology between adeno-associated virus (AAV) serotype 1 and 6 capsids (99.2%), these viruses have different liver transduction profiles when tested as vectors. Examination of...
15.
Grieger J, Snowdy S, Samulski R
J Virol
. 2006 May;
80(11):5199-210.
PMID: 16699000
Adeno-associated virus (AAV) is gaining momentum as a gene therapy vector for human applications. However, there remain impediments to the development of this virus as a vector. One of these...
16.
Grieger J, Samulski R
Adv Biochem Eng Biotechnol
. 2006 Mar;
99:119-45.
PMID: 16568890
Adeno-associated virus (AAV) has emerged as an attractive vector for gene therapy. AAV vectors have successfully been utilized to promote sustained gene expression in a variety of tissues such as...
17.
Grieger J, Samulski R
J Virol
. 2005 Jul;
79(15):9933-44.
PMID: 16014954
The limited packaging capacity of adeno-associated virus (AAV) precludes the design of vectors for the treatment of diseases associated with larger genes. Autonomous parvoviruses, such as minute virus of mice...