Joshua C Doloff
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Explore the profile of Joshua C Doloff including associated specialties, affiliations and a list of published articles.
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51
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1907
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Recent Articles
1.
Steger L, Smit C, Robinson K, Leadingham K, Davidar D, Routkevitch D, et al.
bioRxiv
. 2025 Mar;
PMID: 40060640
Purpose: Replicating spinal cord injury (SCI) in large animals is necessary for evaluating therapeutics for potential human translation, yet there is currently no commercial, standardized device for inducing SCI. We...
2.
Zhu Y, Yao Z, Li S, Ma J, Wei C, Yu D, et al.
bioRxiv
. 2025 Feb;
PMID: 39975373
Hydrogel materials have emerged as versatile platforms for various biomedical applications. Notably, the engineered nanofiber-hydrogel composite (NHC) has proven effective in mimicking the soft tissue extracellular matrix, facilitating substantial recruitment...
3.
Kong J, Yao Z, Stelzel J, Yang Y, Chen J, Feng H, et al.
Adv Healthc Mater
. 2024 Nov;
14(3):e2403094.
PMID: 39580666
The interplay between biomaterials and host immune responses critically determines outcomes in tissue restoration. Recent studies suggest that physicochemical properties of materials can dictate pro-regenerative versus pro-fibrotic responses and have...
4.
Hernandez J, Daniel J, Stelzel J, Prasad N, Soares V, Doloff J
bioRxiv
. 2024 Nov;
PMID: 39554040
Intrauterine adhesions are growths of fibrotic tissue within the uterine cavity and can arise from a variety of tissue-damaging stimuli. Immune cells are known to mediate fibrotic responses, but specific...
5.
Schuster C, Reiche E, Keller P, Hu S, Soares V, Rahmayanti S, et al.
Adv Wound Care (New Rochelle)
. 2024 May;
13(12):615-624.
PMID: 38775428
Nerve scarring after traumatic or iatrogenic exposure can lead to impaired function and pain. Nerve-adjacent biomaterials promoting a regenerative tissue response may help reduce perineural fibrosis. Our prior work suggests...
6.
Reiche E, Keller P, Soares V, Schuster C, Rahmayanti S, Mroueh J, et al.
FASEB J
. 2024 Mar;
38(6):e23561.
PMID: 38530321
Hypertrophic scarring is a major source of morbidity. Sex hormones are not classically considered modulators of scarring. However, based on increased frequency of hypertrophic scarring in patients on testosterone, we...
7.
Livingston N, Hickey J, Sim H, Salathe S, Choy J, Kong J, et al.
Adv Mater
. 2024 Feb;
36(23):e2310043.
PMID: 38358310
T cells are critical mediators of antigen-specific immune responses and are common targets for immunotherapy. Biomaterial scaffolds have previously been used to stimulate antigen-presenting cells to elicit antigen-specific immune responses;...
8.
Quiroz V, Wang Y, Rakoski A, Kasinathan D, Neshat S, Hollister-Lock J, et al.
Adv Biol (Weinh)
. 2024 Jan;
8(8):e2300502.
PMID: 38243878
Biomedical devices such as islet-encapsulating systems are used for treatment of type 1 diabetes (T1D). Despite recent strides in preventing biomaterial fibrosis, challenges remain for biomaterial scaffolds due to limitations...
9.
Zhu Y, Ma J, Shen R, Lin J, Li S, Lu X, et al.
Nat Biomed Eng
. 2023 Dec;
8(5):544-560.
PMID: 38082180
Lipid nanoparticles (LNPs) can be designed to potentiate cancer immunotherapy by promoting their uptake by antigen-presenting cells, stimulating the maturation of these cells and modulating the activity of adjuvants. Here...
10.
Wilson D, Tzeng S, Rui Y, Neshat S, Conge M, Luly K, et al.
Adv Ther (Weinh)
. 2023 Sep;
6(5).
PMID: 37743930
Delivery of self-amplifying mRNA (SAM) has high potential for infectious disease vaccination due its self-adjuvating and dose-sparing properties. Yet a challenge is the susceptibility of SAM to degradation and the...