Joshua B Slee
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Explore the profile of Joshua B Slee including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
127
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Recent Articles
1.
Slee J, McLaughlin J
Biochem Mol Biol Educ
. 2019 Apr;
47(4):417-425.
PMID: 31002463
Often overlooked in many molecular cell biology laboratory and cell culture courses, suspension cells represent an important aspect of molecular cell biology and cell culture. Most primary cell cultures and...
2.
Farwell S, Slee J, Li Y, Lowe-Krentz L
J Vis Exp
. 2017 Mar;
(120).
PMID: 28287514
When novel proteins are identified through affinity-based isolation and bioinformatics analysis, they are often largely uncharacterized. Antibodies against specific peptides within the predicted sequence allow some localization experiments. However, other...
3.
Slee J, Alferiev I, Nagaswami C, Weisel J, Levy R, Fishbein I, et al.
Biomaterials
. 2016 Feb;
87:82-92.
PMID: 26914699
The effectiveness of endovascular stents is hindered by in-stent restenosis (ISR), a secondary re-obstruction of treated arteries due to unresolved inflammation and activation of smooth muscle cells in the arterial...
4.
Pugh R, Slee J, Farwell S, Li Y, Barthol T, Patton W, et al.
J Biol Chem
. 2016 Jan;
291(10):5326-41.
PMID: 26769966
Vascular cell responses to exogenous heparin have been documented to include decreased vascular smooth muscle cell proliferation following decreased ERK pathway signaling. However, the molecular mechanism(s) by which heparin interacts...
5.
Farwell S, Kanyi D, Hamel M, Slee J, Miller E, Cipolle M, et al.
J Biol Chem
. 2016 Jan;
291(10):5342-54.
PMID: 26769965
Despite the large number of heparin and heparan sulfate binding proteins, the molecular mechanism(s) by which heparin alters vascular cell physiology is not well understood. Studies with vascular smooth muscle...
6.
Slee J, Christian A, Levy R, Stachelek S
Polymers (Basel)
. 2015 Feb;
6(10):2526-2551.
PMID: 25705515
Tissue contacting surfaces of medical devices initiate a host inflammatory response, characterized by adsorption of blood proteins and inflammatory cells triggering the release of cytokines, reactive oxygen species (ROS) and...
7.
Slee J, Alferiev I, Levy R, Stachelek S
J Vis Exp
. 2014 Sep;
(90).
PMID: 25178087
The foreign body reaction occurs when a synthetic surface is introduced to the body. It is characterized by adsorption of blood proteins and the subsequent attachment and activation of platelets,...
8.
Gilotti A, Nimlamool W, Pugh R, Slee J, Barthol T, Miller E, et al.
J Cell Physiol
. 2014 Jun;
229(12):2142-52.
PMID: 24911927
Published data provide strong evidence that heparin treatment of proliferating vascular smooth muscle cells results in decreased signaling through the ERK pathway and decreases in cell proliferation. In addition, these...
9.
Slee J, Lowe-Krentz L
J Cell Biochem
. 2012 Oct;
114(4):782-95.
PMID: 23060131
Vascular endothelial cells and their actin microfilaments align in the direction of fluid shear stress (FSS) in vitro and in vivo. To determine whether cofilin, an actin severing protein, is...
10.
Rundell K, Slee J
J Allergy Clin Immunol
. 2008 Aug;
122(2):238-46.
PMID: 18678339
The prevalence of exercise-induced bronchoconstriction is reported to be high among recreational and elite athletes, yet diagnosis is often symptom-based. Indirect challenges such as the laboratory exercise challenge provide objective...