Josh T Cuperus
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Explore the profile of Josh T Cuperus including associated specialties, affiliations and a list of published articles.
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37
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1910
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Recent Articles
1.
Takagi H, Lee N, Hempton A, Purushwani S, Notaguchi M, Yamauchi K, et al.
Dev Cell
. 2025 Feb;
PMID: 40020678
Plants induce the expression of the florigen FLOWERING LOCUS T (FT) in response to seasonal changes. FT is expressed in a distinct subset of phloem companion cells in Arabidopsis. Using...
2.
Zhang J, Greenwood N, Hernandez J, Cuperus J, Huang B, Ryder B, et al.
Cell Chem Biol
. 2025 Feb;
PMID: 39922190
Protein quality control (PQC) is carried out in part by the chaperone Hsp70 in concert with adapters of the J-domain protein (JDP) family. The JDPs, also called Hsp40s, are thought...
3.
Jores T, Mueth N, Tonnies J, Char S, Liu B, Grillo-Alvarado V, et al.
bioRxiv
. 2024 Sep;
PMID: 39345455
Insulators are -regulatory elements that separate transcriptional units, whereas silencers are elements that repress transcription regardless of their position. In plants, these elements remain largely uncharacterized. Here, we use the...
4.
Takagi H, Ito S, Shim J, Kubota A, Hempton A, Lee N, et al.
bioRxiv
. 2024 Sep;
PMID: 39229231
The precise onset of flowering is crucial to ensure successful plant reproduction. The gene () encodes florigen, a mobile signal produced in leaves that initiates flowering at the shoot apical...
5.
Bubb K, Hamm M, Tullius T, Min J, Ramirez-Corona B, Mueth N, et al.
bioRxiv
. 2024 Jul;
PMID: 39026747
The genomes of flowering plants consist largely of transposable elements (TEs), some of which modulate gene regulation and function. However, the repetitive nature of TEs and difficulty of mapping individual...
6.
Gorjifard S, Jores T, Tonnies J, Mueth N, Bubb K, Wrightsman T, et al.
Nat Commun
. 2024 Jul;
15(1):5868.
PMID: 38997252
The 3' end of a gene, often called a terminator, modulates mRNA stability, localization, translation, and polyadenylation. Here, we adapted Plant STARR-seq, a massively parallel reporter assay, to measure the...
7.
Takagi H, Lee N, Hempton A, Purushwani S, Notaguchi M, Yamauchi K, et al.
bioRxiv
. 2024 May;
PMID: 38746097
Seasonal changes in spring induce flowering by expressing the florigen, FLOWERING LOCUS T (FT), in . is expressed in unique phloem companion cells with unknown characteristics. The question of which...
8.
Jores T, Tonnies J, Mueth N, Romanowski A, Fields S, Cuperus J, et al.
Plant Cell
. 2024 Mar;
36(7):2570-2586.
PMID: 38513612
Enhancers are cis-regulatory elements that shape gene expression in response to numerous developmental and environmental cues. In animals, several models have been proposed to explain how enhancers integrate the activity...
9.
Perchlik M, Sasse A, Mostafavi S, Fields S, Cuperus J
RNA
. 2023 Oct;
30(1):52-67.
PMID: 37879864
Intron splicing is a key regulatory step in gene expression in eukaryotes. Three sequence elements required for splicing-5' and 3' splice sites and a branchpoint-are especially well-characterized in , but...
10.
Alexandre C, Bubb K, Schultz K, Lempe J, Cuperus J, Queitsch C
New Phytol
. 2023 Oct;
241(1):253-266.
PMID: 37865885
Isogenic individuals can display seemingly stochastic phenotypic differences, limiting the accuracy of genotype-to-phenotype predictions. The extent of this phenotypic variation depends in part on genetic background, raising questions about the...