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Josh Haipeng Lei

Explore the profile of Josh Haipeng Lei including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 273
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Recent Articles
1.
Li B, Tan Y, Lei J, Deng M, Yu X, Wang X, et al.
Adv Mater . 2025 Feb; :e2416690. PMID: 39935046
Failures of radiotherapy (RT) in adaptive antitumor immunomodulation often associate with recruited tissue-repairing macrophages. Although training these macrophages to phagocytose post-RT cancer cells reverses their protumoral performance, engulfed tumor antigens...
2.
Zhang H, Luo X, Yang W, Wu Z, Zhao Z, Pei X, et al.
Nat Commun . 2024 Nov; 15(1):9559. PMID: 39500904
RNA methylation is an important regulatory process to determine immune cell function but how it affects the anti-tumor activity of CD8 T cells is not fully understood. Here we show...
3.
Wu J, Lei J, Li M, Zhang A, Li Y, Liang X, et al.
Adv Sci (Weinh) . 2024 Sep; 11(43):e2404702. PMID: 39303206
Egg white (EW)-derived hydrogels hold promise as biomaterials for in vitro cell culture due to their ability to mimic the extracellular matrix. However, their highly cross-linked structures restrict their potential...
4.
Li L, Zeng J, Zhang X, Feng Y, Lei J, Xu X, et al.
EMBO Rep . 2024 Feb; 25(3):1361-1386. PMID: 38332150
Non-alcoholic fatty liver disease is a chronic liver abnormality that exhibits high variability and can lead to liver cancer in advanced stages. Hepatic ablation of SIRT6 results in fatty liver...
5.
Feng Y, Zhao M, Wang L, Li L, Lei J, Zhou J, et al.
Cell Death Dis . 2024 Jan; 15(1):34. PMID: 38212325
Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy among primary liver cancers, with an increasing overall incidence and poor prognosis. The intertumoral and intratumoral heterogeneity of ICC makes it...
6.
Lei J, Lee M, Miao K, Huang Z, Yao Z, Zhang A, et al.
Adv Sci (Weinh) . 2023 Dec; 10(36):e2307935. PMID: 38153360
No abstract available.
7.
Zhou J, Tang D, He L, Lin S, Lei J, Sun H, et al.
Pharmacol Res . 2023 Jun; 194:106830. PMID: 37343647
Drug combination therapy is a highly effective approach for enhancing the therapeutic efficacy of anti-cancer drugs and overcoming drug resistance. However, the innumerable possible drug combinations make it impractical to...
8.
Shu X, Li J, Chan U, Su S, Shi C, Zhang X, et al.
Cancer Res . 2023 May; 83(15):2614-2633. PMID: 37227919
Significance: BRCA1 deficiency generates an acidic microenvironment to promote cancer metastasis and immunotherapy resistance that can be reversed using a sialyltransferase inhibitor.
9.
Zhang T, Cheng Q, Lei J, Wang B, Chang Y, Liu Y, et al.
Adv Mater . 2023 May; 35(35):e2302705. PMID: 37216626
Noninvasive fluorescence (FL) imaging and high-performance photocatalytic therapy (PCT) are opposing optical properties that are difficult to combine in a single material system. Herein, a facile approach to introducing oxygen-related...
10.
Li B, Wang G, Miao K, Zhang A, Sun L, Yu X, et al.
Nat Commun . 2023 May; 14(1):2518. PMID: 37130873
Clinical updates suggest conserving metastatic sentinel lymph nodes (SLNs) of breast cancer (BC) patients during surgery; however, the immunoadjuvant potential of this strategy is unknown. Here we leverage an immune-fueling...