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Josephine Zhang

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Articles 6
Citations 49
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Recent Articles
1.
Lemaitre L, Adeniji N, Suresh A, Reguram R, Zhang J, Park J, et al.
Nat Cancer . 2024 Sep; 5(10):1534-1556. PMID: 39304772
Hepatocellular carcinoma (HCC) frequently recurs from minimal residual disease (MRD), which persists after therapy. Here, we identified mechanisms of persistence of residual tumor cells using post-chemoembolization human HCC (n = ...
2.
Lehrich B, Zhang J, Monga S, Dhanasekaran R
J Hepatol . 2023 Dec; 80(3):515-530. PMID: 38104635
The diagnosis and management of hepatocellular carcinoma (HCC) have improved significantly in recent years. With the introduction of immunotherapy-based combination therapy, there has been a notable expansion in treatment options...
3.
Sengupta S, Zhang J, Reed M, Yu J, Kim A, Boronina T, et al.
J Exp Med . 2023 Apr; 220(7). PMID: 37058141
Distinct CD4+ T cell epitopes have been associated with spontaneous control of HIV-1 replication, but analysis of antigen-dependent factors that influence epitope selection is lacking. To examine these factors, we...
4.
Dhanasekaran R, Hansen A, Park J, Lemaitre L, Lai I, Adeniji N, et al.
Cancer Res . 2022 Dec; 83(4):626-640. PMID: 36525476
Significance: Macrophage-mediated immune evasion is a therapeutic vulnerability of MYC-driven cancers, which has implications for prioritizing MYC-driven hepatocellular carcinoma for combination immunotherapy.
5.
Zhang J, Siller-Farfan J
Immunother Adv . 2022 Oct; 2(1):ltac014. PMID: 36284838
Glioblastoma multiforme (GBM) is the most malignant form of cancer in the central nervous system; even with treatment, it has a 5-year survival rate of 7.2%. The adoptive cell transfer...
6.
Sengupta S, Board N, Wu F, Moskovljevic M, Douglass J, Zhang J, et al.
Proc Natl Acad Sci U S A . 2022 Apr; 119(15):e2123406119. PMID: 35394875
HIV-1 infection is incurable due to the persistence of the virus in a latent reservoir of resting memory CD4+ T cells. “Shock-and-kill” approaches that seek to induce HIV-1 gene expression,...