Joseph Xu Zhou
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Explore the profile of Joseph Xu Zhou including associated specialties, affiliations and a list of published articles.
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7
Citations
259
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Recent Articles
1.
Angelini E, Wang Y, Zhou J, Qian H, Huang S
PLoS Comput Biol
. 2022 Jul;
18(7):e1010319.
PMID: 35877695
Intratumor cellular heterogeneity and non-genetic cell plasticity in tumors pose a recently recognized challenge to cancer treatment. Because of the dispersion of initial cell states within a clonal tumor cell...
2.
Zhou J, Samal A, Fouquier dHerouel A, Price N, Huang S
Biosystems
. 2016 Mar;
142-143:15-24.
PMID: 26965665
Progress in cell type reprogramming has revived the interest in Waddington's concept of the epigenetic landscape. Recently researchers developed the quasi-potential theory to represent the Waddington's landscape. The Quasi-potential U(x),...
3.
Zhou J, Pisco A, Qian H, Huang S
PLoS One
. 2014 Dec;
9(12):e110714.
PMID: 25438251
Tumorigenesis is a dynamic biological process that involves distinct cancer cell subpopulations proliferating at different rates and interconverting between them. In this paper we proposed a mathematical framework of population...
4.
Heinaniemi M, Nykter M, Kramer R, Wienecke-Baldacchino A, Sinkkonen L, Zhou J, et al.
Nat Methods
. 2013 Apr;
10(6):577-83.
PMID: 23603899
The distinct cell types of multicellular organisms arise owing to constraints imposed by gene regulatory networks on the collective change of gene expression across the genome, creating self-stabilizing expression states,...
5.
de Back W, Zhou J, Brusch L
J R Soc Interface
. 2012 Nov;
10(79):20120766.
PMID: 23193107
The cell fate decision of multi-potent pancreatic progenitor cells between the exocrine and endocrine lineages is regulated by Notch signalling, mediated by cell-cell interactions. However, canonical models of Notch-mediated lateral...
6.
Zhou J, Aliyu M, Aurell E, Huang S
J R Soc Interface
. 2012 Aug;
9(77):3539-53.
PMID: 22933187
The developmental dynamics of multicellular organisms is a process that takes place in a multi-stable system in which each attractor state represents a cell type, and attractor transitions correspond to...
7.
Zhou J, Brusch L, Huang S
PLoS One
. 2011 Mar;
6(3):e14752.
PMID: 21423725
Cell fate reprogramming, such as the generation of insulin-producing β cells from other pancreas cells, can be achieved by external modulation of key transcription factors. However, the known gene regulatory...