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Joseph Warmus

Explore the profile of Joseph Warmus including associated specialties, affiliations and a list of published articles. Areas
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Citations 227
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Recent Articles
1.
Galatsis P, Caprathe B, Downing D, Gilmore J, Harter W, Hays S, et al.
Bioorg Med Chem Lett . 2010 Aug; 20(17):5089-94. PMID: 20674352
A series of acyloxyalkyl and amidooxyalkyl ketones appended to a carbobenzyloxy aspartic acid core have been prepared. The most potent of these new inhibitors was 4i with a K(i) of...
2.
Ohren J, Chen H, Pavlovsky A, Whitehead C, Zhang E, Kuffa P, et al.
Nat Struct Mol Biol . 2004 Nov; 11(12):1192-7. PMID: 15543157
MEK1 and MEK2 are closely related, dual-specificity tyrosine/threonine protein kinases found in the Ras/Raf/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathway. Approximately 30% of all human cancers have a constitutively activated...