Joseph T Lau
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Explore the profile of Joseph T Lau including associated specialties, affiliations and a list of published articles.
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10
Citations
479
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Recent Articles
1.
Wang S, Del Solar V, Yu X, Antonopoulos A, Friedman A, Agarwal K, et al.
Cell Chem Biol
. 2021 Feb;
28(5):699-710.e5.
PMID: 33609441
There is a critical need to develop small-molecule inhibitors of mucin-type O-linked glycosylation. The best-known reagent currently is benzyl-GalNAc, but it is effective only at millimolar concentrations. This article demonstrates...
2.
Giannini S, Lee-Sundlov M, Rivadeneyra L, Di Buduo C, Burns R, Lau J, et al.
Nat Commun
. 2020 Jan;
11(1):356.
PMID: 31953383
Glycosylation is critical to megakaryocyte (MK) and thrombopoiesis in the context of gene mutations that affect sialylation and galactosylation. Here, we identify the conserved B4galt1 gene as a critical regulator...
3.
Wang S, Gao X, Del Solar V, Yu X, Antonopoulos A, Friedman A, et al.
Cell Chem Biol
. 2018 Oct;
25(12):1519-1532.e5.
PMID: 30344053
Metabolic decoys are synthetic analogs of naturally occurring biosynthetic acceptors. These compounds divert cellular biosynthetic pathways by acting as artificial substrates that usurp the activity of natural enzymes. While O-linked...
4.
Physical Activity in People With Mental Illness in Hong Kong: Application of the Health Belief Model
Mo P K, Chong E, Mak W, Wong S, Lau J
J Sport Exerc Psychol
. 2016 Jul;
38(2):203-8.
PMID: 27390136
Physical activity is associated with various health benefits for people with mental illness (PMI). Very few studies to date have examined the factors associated with physical activity among PMI in...
5.
Cabral M, Silva Z, Ligeiro D, Seixas E, Crespo H, Carrascal M, et al.
Immunology
. 2012 Nov;
138(3):235-45.
PMID: 23113614
Dendritic cells (DCs) play an essential role in immunity against bacteria by phagocytosis and by eliciting adaptive immune responses. Previously, we demonstrated that human monocyte-derived DCs (MDDCs) express a high...
6.
Lee A, Tung S, Chua D, Ngan R, Chappell R, Tung R, et al.
J Natl Cancer Inst
. 2010 Jul;
102(15):1188-98.
PMID: 20634482
Background: Current practice of adding concurrent-adjuvant chemotherapy to radiotherapy (CRT) for treating advanced nasopharyngeal carcinoma is based on the Intergroup-0099 Study published in 1998. However, the outcome for the radiotherapy-alone...
7.
Wierzbicki A, Gil M, Ciesielski M, Fenstermaker R, Kaneko Y, Rokita H, et al.
J Immunol
. 2008 Oct;
181(9):6644-53.
PMID: 18941255
The GD2 ganglioside expressed on neuroectodermal tumor cells has been used as a target for passive and active immunotherapy in patients with malignant melanoma and neuroblastoma. We have reported that...
8.
Nasirikenari M, Segal B, Ostberg J, Urbasic A, Lau J
Blood
. 2006 Jul;
108(10):3397-405.
PMID: 16849643
Elevation of serum sialic acid and the ST6Gal-1 sialyltransferase is part of the hepatic system inflammatory response, but the contribution of ST6Gal-1 has remained unclear. Hepatic ST6Gal-1 elevation is mediated...
9.
Lee A, Lau W, Tung S, Chua D, Chappell R, Xu L, et al.
J Clin Oncol
. 2005 Sep;
23(28):6966-75.
PMID: 16192584
Purpose: This randomized study compared the results achieved by concurrent chemoradiotherapy (CRT) versus radiotherapy (RT) alone for nasopharyngeal carcinoma (NPC) with advanced nodal disease. Patients And Methods: Patients with nonkeratinizing/undifferentiated...
10.
Lau J, Tang A, Tsui H
AIDS
. 2002 Dec;
17(1):105-12.
PMID: 12478075
Objective: This study investigated the consistency of condom use and the prevalence of self-reported sexually transmitted diseases (STD) among male Hong Kong commercial sex clients with respect to the geographical...