Joseph Saad
Overview
Explore the profile of Joseph Saad including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
151
Followers
0
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Recent Articles
1.
Kytola S, Vanttinen I, Vanttinen I, Ruokoranta T, Partanen A, Holopainen A, et al.
Blood
. 2024 Oct;
145(4):409-421.
PMID: 39357056
The B-cell lymphoma 2 inhibitor venetoclax has shown promise for treating acute myeloid leukemia (AML). However, identifying patients likely to respond remains a challenge, especially for those with relapsed/refractory (R/R)...
2.
Eldfors S, Saad J, Ikonen N, Malani D, Vaha-Koskela M, Gjertsen B, et al.
Blood Adv
. 2024 Jan;
8(7):1621-1633.
PMID: 38197948
Monosomy 7 and del(7q) (-7/-7q) are frequent chromosomal abnormalities detected in up to 10% of patients with acute myeloid leukemia (AML). Despite unfavorable treatment outcomes, no approved targeted therapies exist...
3.
Kuusanmaki H, Dufva O, Vaha-Koskela M, Leppa A, Huuhtanen J, Vanttinen I, et al.
Blood
. 2022 Dec;
141(13):1610-1625.
PMID: 36508699
Myeloid neoplasms with erythroid or megakaryocytic differentiation include pure erythroid leukemia, myelodysplastic syndrome with erythroid features, and acute megakaryoblastic leukemia (FAB M7) and are characterized by poor prognosis and limited...
4.
Batcha A, Buckup N, Bamopoulos S, Jurinovic V, Rothenberg-Thurley M, Gittinger H, et al.
Blood Adv
. 2022 Sep;
7(6):1040-1044.
PMID: 36149944
No abstract available.
5.
Okoye-Okafor U, Javarappa K, Tsallos D, Saad J, Yang D, Zhang C, et al.
J Exp Med
. 2022 Sep;
219(11).
PMID: 36053753
Thrombocytopenia, prevalent in the majority of patients with myeloid malignancies, such as myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), is an independent adverse prognostic factor. Azacitidine (AZA), a mainstay...
6.
Zagidullin B, Aldahdooh J, Zheng S, Wang W, Wang Y, Saad J, et al.
Nucleic Acids Res
. 2019 May;
47(W1):W43-W51.
PMID: 31066443
Drug combination therapy has the potential to enhance efficacy, reduce dose-dependent toxicity and prevent the emergence of drug resistance. However, discovery of synergistic and effective drug combinations has been a...
7.
Cazaly E, Saad J, Wang W, Heckman C, Ollikainen M, Tang J
Front Pharmacol
. 2019 Mar;
10:126.
PMID: 30837884
Epigenetic research involves examining the mitotically heritable processes that regulate gene expression, independent of changes in the DNA sequence. Recent technical advances such as whole-genome bisulfite sequencing and affordable epigenomic...