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Joseph R Boyd

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Articles 22
Citations 318
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Recent Articles
1.
OLeary T, Mikucki E, Tangwancharoen S, Boyd J, Frietze S, Helms Cahan S, et al.
bioRxiv . 2025 Jan; PMID: 39829925
Embryogenesis is remarkably robust to temperature variability, yet there is limited understanding of the homeostatic mechanisms that offset thermal effects during early development. Here, we measured the thermal acclimation response...
2.
Tracy K, Prior S, Trowbridge W, Boyd J, Ghule P, Frietze S, et al.
Crit Rev Eukaryot Gene Expr . 2023 Dec; 34(2):61-71. PMID: 38073442
Long non-coding RNA (lncRNA)-mediated control of gene expression contributes to regulation of biological processes that include proliferation and phenotype, as well as compromised expression of genes that are functionally linked...
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Ghule P, Boyd J, Kabala F, Fritz A, Bouffard N, Gao C, et al.
Gene . 2023 Apr; 872:147441. PMID: 37094694
Human Histone Locus Bodies (HLBs) are nuclear subdomains comprised of clustered histone genes that are coordinately regulated throughout the cell cycle. We addressed temporal-spatial higher-order genome organization for time-dependent chromatin...
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Boyd J, Gao C, Quinn K, Fritz A, Stein J, Stein G, et al.
BMC Genomics . 2023 Jan; 24(1):43. PMID: 36698077
Background: Epigenomic profiling assays such as ChIP-seq have been widely used to map the genome-wide enrichment profiles of chromatin-associated proteins and posttranslational histone modifications. Sequencing depth is a key parameter...
6.
Messier T, Boyd J, Gordon J, Tye C, Page N, Toor R, et al.
PLoS One . 2022 Jul; 17(7):e0271725. PMID: 35862394
Selective estrogen receptor modulators (SERMs), including the SERM/SERD bazedoxifene (BZA), are used to treat postmenopausal osteoporosis and may reduce breast cancer (BCa) risk. One of the most persistent unresolved questions...
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Gillis N, Boyd J, Tomczak J, Frietze S, Carr F
Nucleic Acids Res . 2022 Jan; 50(3):1382-1395. PMID: 35037038
Transcriptional regulation in response to thyroid hormone (3,5,3'-triiodo-l-thyronine, T3) is a dynamic and cell-type specific process that maintains cellular homeostasis and identity in all tissues. However, our understanding of the...
8.
McGill M, Richman A, Boyd J, Sabikunnahar B, Lahue K, Montgomery T, et al.
Front Immunol . 2021 Oct; 12:715311. PMID: 34707603
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system, representing the leading cause of non-traumatic neurologic disease in young adults. This disease is three times more...
9.
Rose J, Moskovitz E, Boyd J, Gordon J, Bouffard N, Fritz A, et al.
Oncotarget . 2020 Jul; 11(26):2512-2530. PMID: 32655837
RUNX1 has recently been shown to play an important role in determination of mammary epithelial cell identity. However, mechanisms by which loss of the RUNX1 transcription factor in mammary epithelial...
10.
Park E, Chen J, Moore A, Mangolini M, Santoro A, Boyd J, et al.
Sci Transl Med . 2020 Jan; 12(526). PMID: 31941829
Overcoming drug resistance remains a key challenge to cure patients with acute and chronic B cell malignancies. Here, we describe a stromal cell-autonomous signaling pathway, which contributes to drug resistance...