Joseph P Zackular
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Explore the profile of Joseph P Zackular including associated specialties, affiliations and a list of published articles.
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48
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1745
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Recent Articles
1.
Brunson D, Manzer H, Smith A, Zackular J, Kitten T, Lemos J
bioRxiv
. 2025 Feb;
PMID: 39896487
, a gut commensal, is a leading cause of opportunistic infections. Its virulence is linked to its ability to thrive in hostile environments, which includes host-imposed metal starvation. We recently...
2.
Benitez A, Tanes C, Friedman E, Zackular J, Ford E, Gerber J, et al.
Microbiome
. 2025 Jan;
13(1):21.
PMID: 39856742
Background: The evolving infant gut microbiome influences host immune development and later health outcomes. Early antibiotic exposure could impact microbiome development and contribute to poor outcomes. Here, we use a...
3.
Redding L, Daniel S, Smith A, Keenan O, Barnhart D, Zackular J
Vet Med Sci
. 2024 Nov;
11(1):e70085.
PMID: 39611384
Background: The study of the epidemiology of Clostridioides difficile in populations is greatly facilitated by the ability to isolate and further characterize individual organisms, which requires effective culture protocols. In...
4.
Egan M, de Macedo R, Zackular J
Metallomics
. 2024 Nov;
16(12).
PMID: 39577845
Trace metals are indispensable nutritional factors for all living organisms. During host-pathogen interactions, they serve as crucial resources that dictate infection outcomes. Accordingly, the host uses a defense strategy known...
5.
Ren X, Clark R, Bansah D, Varner E, Tiffany C, Jaswal K, et al.
bioRxiv
. 2024 Nov;
PMID: 39502362
Antimicrobial resistance is an urgent threat to human health. Asymptomatic colonization is often critical for persistence of antimicrobial-resistant pathogens. Gut colonization by the antimicrobial-resistant priority pathogen is associated with increased...
6.
Soto Ocana J, Friedman E, Keenan O, Bayard N, Ford E, Tanes C, et al.
mBio
. 2024 Oct;
15(11):e0153424.
PMID: 39440978
The gut microbiota plays a critical role in human health and disease. Microbial community assembly and succession early in life are influenced by numerous factors. In turn, assembly of this...
7.
Ticer T, Tingler A, Glover J, Dooley S, Kendrick J, Zackular J, et al.
Front Microbiol
. 2024 Oct;
15:1459795.
PMID: 39439940
is a bacterial pathogen that has been implicated in severe gastrointestinal infections. has intrinsic green autofluorescence and the level of this autofluorescence is known to be increased by growth time...
8.
Alameh M, Semon A, Bayard N, Pan Y, Dwivedi G, Knox J, et al.
Science
. 2024 Oct;
386(6717):69-75.
PMID: 39361752
infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)-lipid nanoparticle (LNP) vaccine targeting toxins and virulence factors. This...
9.
Mills E, Smith A, Griffith M, Hewlett K, Pless L, Sundermann A, et al.
medRxiv
. 2024 Aug;
PMID: 39132485
Vancomycin-resistant (VREfm) is a prevalent healthcare-acquired pathogen. Gastrointestinal colonization can lead to difficult-to-treat bloodstream infections with high mortality rates. Prior studies have investigated VREfm population structure within healthcare centers. However,...
10.
Drake M, Daniel S, Baker L, Indugu N, Bittinger K, Dickens C, et al.
Anim Microbiome
. 2024 Jul;
6(1):39.
PMID: 39030654
Zinc is an essential trace element required in the diet of all species. While the effects of zinc have been studied in growing calves, little is known about the effect...