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Joseph P Dewulf

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Articles 23
Citations 185
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Recent Articles
11.
Lucienne M, Gerlini R, Rathkolb B, Calzada-Wack J, Forny P, Wueest S, et al.
Hum Mol Genet . 2023 Jun; 32(17):2717-2734. PMID: 37369025
Inherited disorders of mitochondrial metabolism, including isolated methylmalonic aciduria, present unique challenges to energetic homeostasis by disrupting energy-producing pathways. To better understand global responses to energy shortage, we investigated a...
12.
Manczak B, Verdier M, Dewulf J, Lemaitre F, Haufroid V, Hantson P
Br J Clin Pharmacol . 2023 Feb; 89(5):1686-1689. PMID: 36748282
A 53-year-old woman with a history of acute myeloid leukaemia received a second allogeneic haematopoietic stem cell transplant and was prescribed, among other medications, acyclovir and letermovir (480-mg daily oral...
13.
Van de Wyngaert C, Dewulf J, Collienne C, Laterre P, Hantson P
Case Rep Crit Care . 2022 Aug; 2022:4142539. PMID: 36035086
A 60-year-old man was admitted in the intensive care unit (ICU) for a rapidly progressive respiratory failure due to SARS-CoV-2 infection. He developed numerous complications including acute kidney injury (AKI)...
14.
Ward B, Yombi J, Balligand J, Cani P, Collet J, De Greef J, et al.
Viruses . 2022 Jul; 14(7). PMID: 35891354
More than two years on, the COVID-19 pandemic continues to wreak havoc around the world and has battle-tested the pandemic-situation responses of all major global governments. Two key areas of...
15.
Caligiore F, Zangelmi E, Vetro C, Kentache T, Dewulf J, Veiga-da-Cunha M, et al.
Cell Mol Life Sci . 2022 Jul; 79(8):421. PMID: 35834009
Transaminases play key roles in central metabolism, transferring the amino group from a donor substrate to an acceptor. These enzymes can often act, with low efficiency, on compounds different from...
16.
Dewulf J, Martin M, Marie S, Oguz F, Belkhir L, De Greef J, et al.
Sci Rep . 2022 Jun; 12(1):9959. PMID: 35705608
SARS-CoV-2 causes major disturbances in serum metabolite levels, associated with severity of the immune response. Despite the numerous advantages of urine for biomarker discovery, the potential association between urine metabolites...
17.
de Landsheere F, Saint-Marcoux F, Haufroid V, Dulaurent S, Dewulf J, Boland L, et al.
J Med Toxicol . 2022 Jan; 18(2):155-158. PMID: 35043364
Introduction: Severe metabolic acidosis with elevated anion and osmol gap is suggestive of toxic alcohol ingestion. The absence of detectable methanol or ethylene glycol in the serum could mean that...
18.
Dewulf J, Marie S, Nassogne M
Mol Genet Metab . 2022 Jan; 136(3):190-198. PMID: 34998670
Purines are essential molecules that are components of vital biomolecules, such as nucleic acids, coenzymes, signaling molecules, as well as energy transfer molecules. The de novo biosynthesis pathway starts from...
19.
Goudji C, Schick T, Cherkaoui S, Camaiani M, Dewulf J, Nassogne M, et al.
Clin Chem Lab Med . 2021 Dec; 60(3):85-87. PMID: 34913623
No abstract available.
20.
Dewulf J, Paquay S, Marbaix E, Achouri Y, Van Schaftingen E, Bommer G
J Biol Chem . 2021 Aug; 297(4):101083. PMID: 34419447
The cytosolic enzyme ethylmalonyl-CoA decarboxylase (ECHDC1) decarboxylates ethyl- or methyl-malonyl-CoA, two side products of acetyl-CoA carboxylase. These CoA derivatives can be used to synthesize a subset of branched-chain fatty acids...