Joseph P Dewulf
Overview
Explore the profile of Joseph P Dewulf including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
185
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Recent Articles
1.
Michel L, Esfahani H, De Mulder D, Verdoy R, Ambroise J, Roelants V, et al.
Circulation
. 2025 Mar;
PMID: 40071326
Background: Cardiac β3-adrenergic receptors (ARs) are upregulated in diseased hearts and mediate antithetic effects to those of β1AR and β2AR. β3AR agonists were recently shown to protect against myocardial remodeling...
2.
Decru B, Lys M, Truijens K, Mercier N, Papadopoulos J, Rymen D, et al.
Mol Genet Metab
. 2025 Jan;
144(1):109007.
PMID: 39798988
Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2) deficiency is a rare, potentially life-threatening autosomal recessive disorder resulting from mutations in the HMGCS2 gene, leading to impaired ketogenesis. We systematically reviewed the clinical...
3.
Paquay S, Duraffourd J, Bury M, Heremans I, Caligiore F, Gerin I, et al.
Cell Mol Life Sci
. 2024 Aug;
81(1):367.
PMID: 39174697
Hydroxylated fatty acids are important intermediates in lipid metabolism and signaling. Surprisingly, the metabolism of 4-hydroxy fatty acids remains largely unexplored. We found that both ACAD10 and ACAD11 unite two...
4.
Ward B, Pyr Dit Ruys S, Balligand J, Belkhir L, Cani P, Collet J, et al.
J Proteome Res
. 2024 Aug;
23(9):3806-3822.
PMID: 39159935
Plasma proteomics is a precious tool in human disease research but requires extensive sample preparation in order to perform in-depth analysis and biomarker discovery using traditional data-dependent acquisition (DDA). Here,...
5.
Wilson M, Kentache T, Althoff C, Schulz C, de Bettignies G, Cabrera G, et al.
Cell
. 2024 Jun;
187(14):3784.
PMID: 38870945
No abstract available.
6.
Wilson M, Kentache T, Althoff C, Schulz C, de Bettignies G, Cabrera G, et al.
Cell
. 2024 May;
187(14):3585-3601.e22.
PMID: 38821050
Dolichol is a lipid critical for N-glycosylation as a carrier for activated sugars and nascent oligosaccharides. It is commonly thought to be directly produced from polyprenol by the enzyme SRD5A3....
7.
Everard E, Laeremans H, Boemer F, Marie S, Vincent M, Dewulf J, et al.
Eur J Paediatr Neurol
. 2024 Feb;
49:60-65.
PMID: 38377647
Fatty acid oxidation (FAO) disorders are autosomal recessive genetic disorders affecting either the transport or the oxidation of fatty acids. Acute symptoms arise during prolonged fasting, intercurrent infections, or intense...
8.
Dewulf J, Chevalier N, Marie S, Veiga-da-Cunha M
Mol Genet Metab
. 2024 Feb;
140(3):107712.
PMID: 38353183
Glycogen storage disease type Ib (GSD1b) and G6PC3-deficiency are rare autosomal recessive diseases caused by inactivating mutations in SLC37A4 (coding for G6PT) and G6PC3, respectively. Both diseases are characterized by...
9.
Nassogne M, Marie S, Dewulf J
Eur J Paediatr Neurol
. 2023 Dec;
48:69-77.
PMID: 38056117
Purines and pyrimidines are essential components as they are the building blocks of vital molecules, such as nucleic acids, coenzymes, signalling molecules, as well as energy transfer molecules. Purine and...
10.
Degraeve A, Bindels L, Haufroid V, Moudio S, Boland L, Delongie K, et al.
Clin Pharmacol Ther
. 2023 Oct;
115(1):104-115.
PMID: 37846607
Clinical use of tacrolimus (TAC), an essential immunosuppressant following transplantation, is complexified by its high pharmacokinetic (PK) variability. The gut microbiota gains growing interest but limited investigations have evaluated its...