Joseph P Bielawski
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Explore the profile of Joseph P Bielawski including associated specialties, affiliations and a list of published articles.
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61
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1865
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Recent Articles
1.
Magpali L, Bielawski J
Trends Genet
. 2023 Mar;
39(6):436-438.
PMID: 36997429
Gigantism is prevalent in animals, but it has never reached more extreme levels than in aquatic mammals such as whales, dolphins, and porpoises. A new study by Silva et al....
2.
MacDonald T, Dunn K, MacDonald J, Langille M, Van Limbergen J, Bielawski J, et al.
Front Cell Infect Microbiol
. 2023 Mar;
13:1102501.
PMID: 36909730
Introduction: Most children with leukemia and lymphoma experience febrile neutropenia. These are treated with empiric antibiotics that include β-lactams and/or vancomycin. These are often administered for extended periods, and the...
3.
Community-level evolutionary processes: Linking community genetics with replicator-interactor theory
Lean C, Doolittle W, Bielawski J
Proc Natl Acad Sci U S A
. 2022 Nov;
119(46):e2202538119.
PMID: 36322791
Understanding community-level selection using Lewontin's criteria requires both community-level inheritance and community-level heritability, and in the discipline of community and ecosystem genetics, these are often conflated. While there are existing...
4.
Verburgt C, Dunn K, Ghiboub M, Lewis J, Wine E, Sigall Boneh R, et al.
J Crohns Colitis
. 2022 Sep;
17(1):61-72.
PMID: 36106847
Background And Aims: Nutritional therapy with the Crohn's Disease Exclusion Diet + Partial Enteral Nutrition [CDED+PEN] or Exclusive Enteral Nutrition [EEN] induces remission and reduces inflammation in mild-to-moderate paediatric Crohn's...
5.
Dunn K, MacDonald T, Rodrigues G, Forbrigger Z, Bielawski J, Langille M, et al.
Front Cell Infect Microbiol
. 2022 Aug;
12:924707.
PMID: 35967843
Due to decreased immunity, both antibiotics and antifungals are regularly used in pediatric hematologic-cancer patients as a means to prevent severe infections and febrile neutropenia. The general effect of antibiotics...
6.
Bjorndahl P, Bielawski J, Liu L, Zhou W, Gu H
Appl Environ Microbiol
. 2022 Feb;
88(6):e0214621.
PMID: 35138931
Survival analysis is a prolific statistical tool in medicine for inferring risk and time to disease-related events. However, it is underutilized in microbiome research to predict microbial community-mediated events, partly...
7.
Youssef N, Susko E, Roger A, Bielawski J
Mol Biol Evol
. 2022 Feb;
39(3).
PMID: 35134997
Site-specific amino acid preferences are influenced by the genetic background of the protein. The preferences for resident amino acids are expected to, on average, increase over time because of replacements...
8.
Youssef N, Susko E, Roger A, Bielawski J
Protein Sci
. 2021 Jul;
30(10):2009-2028.
PMID: 34322924
Amino acid preferences vary across sites and time. While variation across sites is widely accepted, the extent and frequency of temporal shifts are contentious. Our understanding of the drivers of...
9.
Dunn K, Forbrigger Z, Connors J, Rahman M, Cohen A, Van Limbergen J, et al.
Leuk Lymphoma
. 2021 Jul;
62(13):3244-3255.
PMID: 34279176
Treatment of pediatric acute lymphoblastic leukemia (ALL) with pegaspargase exploits ALL cells dependency on asparagine. Pegaspargase depletes asparagine, consequentially affecting aspartate, glutamine and glutamate. The gut as a confounding source...
10.
Brunet T, Doolittle W, Bielawski J
Stud Hist Philos Sci
. 2021 Jun;
87:125-135.
PMID: 34111815
Fitness contribution alone should not be the criterion of 'function' in molecular biology and genomics. Disagreement over the use of 'function' in molecular biology and genomics is still with us,...