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Joseph M Wallace

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Articles 110
Citations 1306
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Recent Articles
1.
Arnhart M, Surowiec R, Allen M, Wallace J, Pyrak-Nolte L, Howarter J, et al.
J Mech Behav Biomed Mater . 2025 Feb; 166:106956. PMID: 40020569
Understanding bone strength is important when assessing bone diseases and their treatment. Bending experiments are often used to determine strength. Then, flexural stresses are calculated from elastic bending theory. With...
2.
Reul O, Surowiec R, Chowdhury N, Segvich D, Wallace J
J Mech Behav Biomed Mater . 2025 Feb; 165:106950. PMID: 39961220
The use of compressive axial tibial loading for evaluation of bone adaptation and mechanotransduction has become a common technique in recent years. Despite its popularity, it only produces a single...
3.
Kohler R, Segvich D, Reul O, Metzger C, Allen M, Wallace J
Bone . 2025 Jan; 194:117415. PMID: 39884489
Comorbid diabetes and chronic kidney disease create a complex disease state with multi-faceted impacts on bone health, primarily reduced bone mass and tissue quality. To reduce fracture risk in this...
4.
Pianeta R, Deosthale P, Sanz N, Kohler R, Okpara C, Arnett M, et al.
JBMR Plus . 2024 Dec; 9(1):ziae144. PMID: 39677924
The R47H variant of the triggering receptor expressed on myeloid cells 2 (TREM2) is a risk factor for Alzheimer's disease in humans and leads to lower bone mass accrual in...
5.
Gallaway G, Surowiec R, Allen M, Wallace J, Pyrak-Nolte L, Howarter J, et al.
J Biomech . 2024 Oct; 176:112359. PMID: 39413449
Quasi-brittle fracture mechanics is used to evaluate fracture of human cortical bone in aging. The approach is demonstrated using cortical bone bars extracted from one 92-year-old human male cadaver. In-situ...
6.
Ramirez G, Okpara C, Arnett M, Segvich D, Deosthale P, Gonzalez P, et al.
J Bone Miner Res . 2024 Sep; 39(11):1659-1672. PMID: 39255371
Vertebrate sexual dimorphism is ascribed to the presence of testes or ovaries, and, hence, to the secretion of gonad-specific hormones. However, mounting evidence indicates that sex differences in tissues and...
7.
LaCombe J, Sloan K, Thomas J, Blackwell M, Crawford I, Bishop F, et al.
Dis Model Mech . 2024 Aug; 17(9). PMID: 39136051
Skeletal insufficiency affects all individuals with Down syndrome (DS) or trisomy 21 and may alter bone strength throughout development due to a reduced period of bone formation and early attainment...
8.
Williams D, Taylor 4th L, Miter G, Sheiman J, Wallace J, Allen M, et al.
ACS Med Chem Lett . 2024 Jun; 15(6):879-884. PMID: 38894928
Methodology is described for the synthesis of C derivatives of raloxifene, a prescribed drug for the treatment and prevention of osteoporosis. Studies have explored the incorporation of electron-withdrawing substituents at...
9.
LaCombe J, Sloan K, Thomas J, Blackwell M, Crawford I, Wallace J, et al.
bioRxiv . 2024 Jun; PMID: 38826419
Skeletal insufficiency affects all individuals with Down syndrome (DS) or Trisomy 21 (Ts21) and may alter bone strength throughout development due to a reduced period of bone formation and early...
10.
Kohler R, Segvich D, Reul O, Metzger C, Allen M, Wallace J
Bone Rep . 2024 May; 21:101774. PMID: 38778834
As international incidence of diabetes and diabetes-driven comorbidities such as chronic kidney disease (CKD) continue to climb, interventions are needed that address the high-risk skeletal fragility of what is a...